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1.
Int J Environ Res Public Health ; 19(22)2022 Nov 10.
Статья | MEDLINE | ID: covidwho-2110082

Реферат

BACKGROUND: Several quantitative studies have found a decline in physical activity in response to COVID-19 pandemic restrictions. The aim of the present study was to use large-scale free text survey data to qualitatively gain a more in-depth understanding of the impact of the COVID-19 pandemic on physical activity, then map barriers and facilitators to the Capability, Opportunity, Motivation, and Behaviour (COM-B) Model of Behaviour to aid future intervention development. METHODS: 17,082 participants provided a response to the free text module, and data from those who mentioned a physical activity related word in any context were included. Data were analysed using thematic analysis and key themes identified. RESULTS: 5396 participants provided 7490 quotes related to physical activity. The sample were predominately female (84%), white (British/Irish/Other) (97%) and aged <60 years (57%). Seven key themes were identified: the importance of outdoor space, changes in daily routine, COVID-19 restrictions prevented participation, perceived risks or threats to participation, the importance of physical health, the importance of physical activity for mental health and the use of technology. CONCLUSION: Future physical activity interventions could encourage people to walk outdoors, which is low cost, flexible, and accessible to many. Developing online resources to promote and support physical activity provides a flexible way to deliver quality content to a large audience.


Тема - темы
COVID-19 , Humans , Female , COVID-19/epidemiology , Pandemics , Exercise/psychology , Surveys and Questionnaires , United Kingdom/epidemiology
2.
Int J Environ Res Public Health ; 19(22)2022 Nov 09.
Статья в английский | MEDLINE | ID: covidwho-2110077

Реферат

Studies suggest that persistent symptoms after COVID-19 (long COVID) influence functioning and activities of daily living (ADL). However, it is still uncertain how and to what extent. This study aimed to describe patient-reported mental fatigue, ADL problems, ADL ability, sick leave and functional status among patients with long COVID. In this cross-sectional study, 448 patients, ≥18 years old and referred to occupational therapy at a Danish Post-COVID-19 Clinic, were included. Mental fatigue was measured by the Mental Fatigue Scale, ADL problems and ability were measured by the Canadian Occupational Performance Measure, sick leave was self-reported and functional status was evaluated by the Post-COVID-19 Functional Status Scale. Mean age was 46.8 years, 73% of the patients were female, and 75% suffered from moderate to severe mental fatigue. The majority reported difficulties performing productive and leisure activities. The median performance and satisfaction scores were 4.8 and 3, respectively. In total, 56% of the patients were on sick leave, and 94% were referred to rehabilitation. A decrease in functional status was found between pre-COVID-19 and assessment. Conclusively, the patients were highly affected in their everyday life and had distinct rehabilitation needs. Future research is needed to address causalities and rehabilitation for this patient group.


Тема - темы
COVID-19 , Sick Leave , Humans , Female , Middle Aged , Adolescent , Male , Activities of Daily Living , Cross-Sectional Studies , COVID-19/epidemiology , Functional Status , Canada , Mental Fatigue/epidemiology
3.
Int J Environ Res Public Health ; 19(22)2022 Nov 09.
Статья в английский | MEDLINE | ID: covidwho-2110076

Реферат

With the arrival of COVID-19, educational systems have had to adapt to the social and health situation immediately. This led to the appearance of the asynchronous teaching model. Throughout the pandemic, at the educational level, we can distinguish three phases, eminently online, hybrid, and finally, face-to-face. However, the perception of educational quality in these three educational moments, taking into account the psychometric profile and gender, has not been studied. Thus, 1093 university students from Ibero-American countries were analyzed. Through a questionnaire, demographic, academic, and psychological variables were analyzed at three moments during the evolution of the pandemic. Data suggest that, during the lockdown phase, while teaching was eminently online, students presented higher levels of stress and higher difficulty of learning; class attendance, convenience, preferred method of learning, grading score, and motivation were lower, compared to other phases of teaching (hybrid and face-to-face). During this period, females presented higher stress levels than males, as well as higher levels of anxiety and loneliness, without gender differences among the other studied variables. During the hybrid and face-to-face phases, male students presented higher values in the results of difficulty learning and demanding activities. No differences were seen regarding motivation, synchronous class attendance, learning level, grades, convenience, or preferred learning method. The results from the present study suggest that, despite the effect of the pandemic on mental health, asynchronous education is postulated as an effective teaching-learning alternative. Yet, a special focus should be given to female students.


Тема - темы
COVID-19 , Humans , Male , Female , United States , COVID-19/epidemiology , Pandemics , Sex Factors , Universities , Communicable Disease Control , Students
4.
Int J Environ Res Public Health ; 19(22)2022 Nov 08.
Статья в английский | MEDLINE | ID: covidwho-2110072

Реферат

BACKGROUND: Several reports from around the world have reported that some patients who have recovered from COVID-19 have experienced a range of persistent or new clinical symptoms after a SARS-CoV-2 infection. These symptoms can last from weeks to months, impacting everyday functioning to a significant number of patients. METHODS: A cross-sectional analysis based on an online, self-reporting questionnaire was conducted in Ecuador from April to July 2022. Participants were invited by social media, radio, and TV to voluntarily participate in our study. A total of 2103 surveys were included in this study. We compared socio-demographic variables and long-term persisting symptoms at low (<2500 m) and high altitude (>2500 m). RESULTS: Overall, 1100 (52.3%) responders claimed to have Long-COVID symptoms after SARS-CoV-2 infection. Most of these were reported by women (64.0%); the most affected group was young adults between 21 to 40 years (68.5%), and most long-haulers were mestizos (91.6%). We found that high altitude residents were more likely to report persisting symptoms (71.7%) versus those living at lower altitudes (29.3%). The most common symptoms were fatigue or tiredness (8.4%), hair loss (5.1%) and difficulty concentrating (5.0%). The highest proportion of symptoms was observed in the group that received less than 2 doses. CONCLUSIONS: This is the first study describing post-COVID symptoms' persistence in low and high-altitude residents. Our findings demonstrate that women, especially those aging between 21-40, are more likely to describe Long-COVID. We also found that living at a high altitude was associated with higher reports of mood changes, tachycardia, decreased libido, insomnia, and palpitations compared to lowlanders. Finally, we found a greater risk to report Long-COVID symptoms among women, those with previous comorbidities and those who had a severer acute SARS-CoV-2 infection.


Тема - темы
Altitude , COVID-19 , Young Adult , Humans , Female , COVID-19/epidemiology , Cross-Sectional Studies , SARS-CoV-2
5.
Int J Environ Res Public Health ; 19(22)2022 Nov 08.
Статья в английский | MEDLINE | ID: covidwho-2110069

Реферат

The COVID-19 pandemic caused serious health problems that affected people around the globe. This study aims to understand the physical distress (PhyD), psychological distress (PsyD), and coping experiences among people infected with COVID-19, develop a grounded theory, and examine PhyD, PsyD, and coping among people infected with COVID-19. A sequential exploratory mixed methods strategy is employed. A qualitative procedure is based on a grounded theory; data collection includes observation and in-depth interviews with 25 participants, aged 18 years and above. The quantitative one included 180 participants. Content analysis was applied using the Strauss and Corbin method, and ATLAS.ti software. Descriptive statistics, Pearson's correlation, and the independent t-test were used. Results: The six major themes, including (1) severity of COVID-19 symptoms, (2) death anxiety, (3) uncertainty, (4) barrier to healthcare access, (5) compliance and self-regulation coping (6) post-COVID-19 effects. PhyD, PsyD, and coping were all at a moderate level. The relationship between PhyD, PsyD, and coping was positive. The prevalence in post-COVID-19 effects was 70% (95% CI 63.3-76.4%). There were higher amounts in women than men. The most frequent residual symptoms were decreased activity tolerance (40%), fatigue (33.3%), anxiety and fear of abnormal lungs (33.3%), dyspnea (27.8%), allergy (24.4%), and lung impairment (22.2%). Moreover, the prevalence of more than two symptoms was 54% (95% CI 47.2-61.7%). This study considers that the healthcare providers should be concerned with sufficient healthcare services. Interventions are needed for supporting their recovery from COVID-19 effects.


Тема - темы
COVID-19 , Psychological Distress , Male , Humans , Female , COVID-19/epidemiology , Pandemics , Health Services , Adaptation, Psychological
6.
Int J Environ Res Public Health ; 19(22)2022 Nov 08.
Статья в английский | MEDLINE | ID: covidwho-2110063

Реферат

Evidence about how the pandemic affected household violence in Canada is mixed, but inarguably, the risk factors increased. This study used data from the 2020 Canadian Perspective Survey Series and the 2020 and 2021 Surveys of COVID-19 and Mental Health to examine the following: changes in the prevalence of concern about violence in individuals' own homes during the pandemic; the characteristics of those who expressed concern; and the prevalence of concerns for specific household members. Among Canadians, the prevalence of concern about violence in individuals' own homes decreased significantly between July and Fall 2020 (5.8% to 4.2%). Among women, the characteristics that were significantly associated with higher adjusted odds of concern about household violence included larger household size and lower household income. Lower education among women was associated with lower adjusted odds of concern. The associations with higher adjusted odds of concern among men included: being an immigrant, larger household size, and lower household income. From Fall 2020 to Spring 2021, the prevalence of concerns for oneself and for a child/children increased (1.7% to 2.5% and 1.0% to 2.5%, respectively), but concern for other adults in the household decreased (1.9% to 1.2%). Ongoing surveillance is needed to understand vulnerable populations' exposure to household violence and to inform policies and programs.


Тема - темы
COVID-19 , Male , Child , Adult , Humans , Female , COVID-19/epidemiology , Pandemics , Cross-Sectional Studies , Canada/epidemiology , Violence
7.
Int J Environ Res Public Health ; 19(22)2022 Nov 08.
Статья в английский | MEDLINE | ID: covidwho-2110062

Реферат

BACKGROUND: The COVID-19 pandemic has disastrous impacts that impose the cultivation of knowledge and motivation of self-protection to foster disease containment. AIM: Evaluate the effect of digital self-learned educational intervention about COVID-19 using the protection motivation theory (PMT) on non-health students' knowledge and self-protective behaviors at Saudi Electronic University (SEU). METHODS: A quasi-experimental study was accomplished at three randomly chosen branches of SEU (Riyadh, Dammam, Jeddah) using a multistage sampling technique to conveniently select 219 students. An electronic self-administered questionnaire was used, which included three scales for assessing the students' knowledge, self-protective behaviors, and the constructs of the PMT. The educational intervention was designed using four stages: need assessment, planning, implementation, and evaluation. A peer-reviewed digital educational content was developed after assessing the participants' educational needs using the pretest. Then, distributed through their university emails. A weekly synchronous Zoom cloud meeting and daily key health messages were shared with them. Finally, the post-test was conducted after two months. RESULTS: The mean participants' age (SD) among the experimental group was 28.94 (6.719), and the control group was 27.80 (7.256), with a high female percentage (63.4%, 73.8%) and a previous history of direct contact with verified COVID-19 patients (78.6%, 69.2%), respectively. A significant positive mean change (p = 0.000) was detected in the total COVID-19 knowledge of the experimental group post-intervention, either when it was adjusted for the covariates effect of the control group (F1 = 630.547) or the pretest (F1 = 8.585) with a large effect size (η2 = 0.745, η2 = 0.268, respectively). The same was proved by the ANCOVA test for the total self-protective behaviors either when it adjusted for the covariates effect of the control group (F1 = 66.671, p = 0.000) or the pretest (F1 = 5.873, p = 0.020) with a large effect size (η2 = 0.236, η2 = 0.164, respectively). The ANCOVA test proved that post-intervention, all the PMT constructs (perceived threats, reward appraisal, efficacy appraisal, response cost, and protection intention) and the total PMT score were significantly improved (p = 0.000) among the experimental group either when adjusted for the covariates effect of the control group (F1 = 83.835) or the pretest (F1 = 11.658) with a large effect size (η2 = 0.280, η2 = 0.561, respectively). CONCLUSIONS: The digital PMT-based self-learned educational intervention effectively boosts non-health university students' COVID-19 knowledge, protection motivation, and self-protective behaviors. Thus, PMT is highly praised as a basis for COVID-19-related educational intervention and, on similar occasions, future outbreaks.


Тема - темы
COVID-19 , Motivation , Humans , Female , Universities , COVID-19/epidemiology , COVID-19/prevention & control , Pandemics , Saudi Arabia/epidemiology , Self Efficacy , Students , Electronics
8.
Int J Environ Res Public Health ; 19(19)2022 Sep 25.
Статья в английский | MEDLINE | ID: covidwho-2110058

Реферат

University education is still being impacted two years after the COVID-19 outbreak. We performed a rapid survey in February 2022 at two public universities in Vietnam to examine the effects of the pandemic on well-being and the factors that may associate with online class preference among university students as well as to investigate the need for support to improve resilience. A web-based survey included 1589 undergraduate students in total. Both quantitative and qualitative data analysis was carried out. Overall, approximately a quarter of respondents said that they perceived an influence on their health, 42.9% expressed stress, and more than 70% reported worrying about the future. In total, 61.9% of the respondents reported having satisfaction with online classes, while over half of them preferred a program of 50% online classes. Students who live in an urban area, are female, have had pre-COVID-19 campus life experience, have decreased income, and/or experience low online satisfaction and over-information may be in need of more support. The results show implications for universities to consider policies addressing well-being and post-pandemic online education. Providing support to university students to improve their resilience against the impact on their studying, campus life, health, and well-being should be prioritized during and post-pandemic.


Тема - темы
COVID-19 , COVID-19/epidemiology , Female , Humans , Male , Pandemics , Students , Universities , Vietnam/epidemiology
9.
Int J Environ Res Public Health ; 19(19)2022 Sep 22.
Статья в английский | MEDLINE | ID: covidwho-2110054

Реферат

OBJECTIVE: The current study will evaluate the association that the COVID-19 pandemic has had with health-care workers and identify the factors that influenced the female gender being more affected. METHODS: This is a cross-sectional study conducted in two hospitals in Arequipa (a Peruvian city). The participants were health-care workers. We applied a questionnaire with sociodemographic information and three scales: the Generalized Anxiety Disorder-7, the Patient Health Questionnaire-9, and the Primary Care Post-Traumatic Stress Disorder (PTSD) Screen for DSM-5. The main outcomes were anxiety, depression, and PTSD scores. The exposure of interest was gender. The scores of the scales were estimated by medians and percentiles 25-75 (p25-p75), and we used linear regression to estimate the crude and adjusted coefficients and their respective confidence intervals at 95% (CI 95%). RESULTS: There were 109 participants, and 43.1% were women. The anxiety, depression, and PTSD median (p25-p75) scores in the study population were 6 (2-11), 6 (2-10), and 1 (0-3), respectively. The adjusted analysis showed that the female sex had 4.48 (CI 95% 2.95-6.00), 4.50 (CI 95% 2.39-6.62), and 1.13 (CI 95% 0.50-1.76) higher points on average for the scales of anxiety, depression, and PTSD symptoms in comparison to males, respectively. CONCLUSIONS: Female health-care workers showed increased scores of mental health issues in comparison to male health-care workers.


Тема - темы
COVID-19 , Stress Disorders, Post-Traumatic , Anxiety/epidemiology , Anxiety/psychology , Anxiety Disorders/epidemiology , COVID-19/epidemiology , Cross-Sectional Studies , Depression/epidemiology , Depression/psychology , Female , Humans , Male , Pandemics , Peru/epidemiology , SARS-CoV-2 , Stress Disorders, Post-Traumatic/epidemiology , Stress Disorders, Post-Traumatic/psychology
10.
Curr Oncol ; 29(11): 8565-8578, 2022 Nov 11.
Статья в английский | MEDLINE | ID: covidwho-2109972

Реферат

Since the beginning of the COVID-19 pandemic, the use of telehealth was rapidly implemented without previous evidence. The ONCOTELEMD study aimed to evaluate the opinion of patients attended via telemedicine during this period and to study factors that condition patient preferences on its use. Included patients had a confirmed cancer diagnosis and were contacted by telephone between 13 March and 30 April 2020, in the Medical Oncology Service of Hospital Parc Taulí, Sabadell. A 12-question survey was presented to them between 4 February and 19 April 2021. Statistical analysis was carried out using chi-square and multivariable logistic regression tests. Six hundred forty-six patients were included; 487 responded to the survey. The median age was 68 years (27-90), 55.2% were female. Most patients had a surveillance visit (65.3%) and were diagnosed with colorectal or breast cancer (43% and 26.5%, respectively); 91.8% of patients were satisfied, and 60% would accept the use of telemedicine beyond the pandemic. Patients aged more than 50 years (OR 0.40; 95% CI, 0.19-0.81; p = 0.01) and diagnosed with breast cancer (OR 0.45; 95% CI, 0.26-0.69; p < 0.001) were less predisposed to adopt telehealth in the future. Patients agreed to be informed via telehealth of scan or lab results (62% and 84%, respectively) but not of new oral or endovenous treatments (52% and 33.5%, respectively). Additionally, 75% of patients had a medium or low-null technologic ability, and 51.3% would only use the telephone or video call to contact health professionals. However, differences were found according to age groups (p < 0.0001). In total, patients surveyed were satisfied with telemedicine and believed telehealth could have a role following the COVID-19 pandemic. Moreover, our results remark on the importance of individualizing the use of telehealth, showing relevant data on patient preferences and digital literacy.


Тема - темы
Breast Neoplasms , COVID-19 , Telemedicine , Humans , Female , Aged , Male , COVID-19/epidemiology , Pandemics , Telemedicine/methods , Health Personnel
11.
Curr Oncol ; 29(11): 8483-8500, 2022 Nov 08.
Статья в английский | MEDLINE | ID: covidwho-2109971

Реферат

Rapid and efficient communication regarding quickly evolving medical information was paramount for healthcare providers and patients throughout the COVID-19 pandemic. Over the last several years, social media platforms such as Twitter have emerged as important tools for health promotion, virtual learning among healthcare providers, and patient support. We conducted a qualitative thematic content analysis on tweets using the hashtags #BreastSurgery, #BreastCancer, #BreastOncology, #Pandemic, and #COVID19. Advocacy organizations were the most frequent authors of tweets captured in this dataset, and most tweets came from the United States of America (64%). Seventy-three codes were generated from the data, and, through iterative, inductive analysis, three major themes were developed: patient hesitancy and vulnerability, increased efforts in knowledge sharing, and evolving best practices. We found that Twitter was an effective way to share evolving best practices, education, and collective experiences among key stakeholders. As Twitter is increasingly used as a tool for health promotion and knowledge translation, a better understanding of how key stakeholders engage with healthcare-related topics on the platform can help optimize the use of this powerful tool.


Тема - темы
Breast Neoplasms , COVID-19 , Social Media , Humans , United States , Female , COVID-19/epidemiology , Pandemics , Breast Neoplasms/therapy
12.
Front Public Health ; 10: 1007637, 2022.
Статья в английский | MEDLINE | ID: covidwho-2109884

Реферат

Introduction: Reports of unexpected side effects have accompanied the vaccination of larger proportions of the population against coronavirus disease 2019 (COVID-19), including a few cases of inflammatory myopathy (IM). In a bid to improve understanding of the clinical course of vaccine complications, a systematic review of reported cases of IM following COVID-19 vaccination has been conducted. Methods: The PRISMA guideline 2020 was followed. Two independent investigators systematically searched PubMed and Embase to identify relevant studies published up to July 2022, using the following keywords: COVID-19 Vaccine, inflammatory myositis. The Joanna Briggs Institute critical appraisal tools were used for the risk of bias. Results: A total of 24 articles presenting clinical features of 37 patients with IM following COVID-19 vaccine were identified. Female patients composed 59.5% of cases and 82.4% had been vaccinated with BNT162b2 or ChAdOx1. Onset of symptoms occurred within 2 weeks of the first or second vaccine dose in 29 (85.3%) patients and included muscular weakness in 54.1% and skin rash in 71.4% of patients. Myositis specific autoantibodies (MSAs) and myositis associated autoantibodies (MAAs) were reported in 28 patients. Specific clinical subtypes of myositis, reported in 27 patients, included 22 (81.5%) cases of dermatomyositis (DM) and 3 (11.1%) cases of immune-mediated necrotizing myopathy (IMNM). Following treatment, 32 (86.5%) patients showed improvement on follow-up. Conclusion: COVID-19 vaccine may induce various clinical myositis subtypes and related antibodies. Muscular weakness was the most common presenting symptom. Clinicians should be aware of this unexpected adverse event following COVID-19 vaccination and arrange for appropriate management. Systematic review registration: INPLASY https://inplasy.com/inplasy-2022-9-0084/ [INPLASY202290084].


Тема - темы
COVID-19 , Myositis , Female , Humans , Autoantibodies , BNT162 Vaccine , COVID-19/prevention & control , COVID-19 Vaccines/adverse effects , Muscle Weakness , Myositis/etiology , Vaccination
13.
JMIR Public Health Surveill ; 8(11): e40751, 2022 Nov 18.
Статья в английский | MEDLINE | ID: covidwho-2109572

Реферат

BACKGROUND: As of August 25, 2021, Jiangsu province experienced the largest COVID-19 outbreak in eastern China that was seeded by SARS-CoV-2 Delta variants. As one of the key epidemiological parameters characterizing the transmission dynamics of COVID-19, the incubation period plays an essential role in informing public health measures for epidemic control. The incubation period of COVID-19 could vary by different age, sex, disease severity, and study settings. However, the impacts of these factors on the incubation period of Delta variants remains uninvestigated. OBJECTIVE: The objective of this study is to characterize the incubation period of the Delta variant using detailed contact tracing data. The effects of age, sex, and disease severity on the incubation period were investigated by multivariate regression analysis and subgroup analysis. METHODS: We extracted contact tracing data of 353 laboratory-confirmed cases of SARS-CoV-2 Delta variants' infection in Jiangsu province, China, from July to August 2021. The distribution of incubation period of Delta variants was estimated by using likelihood-based approach with adjustment for interval-censored observations. The effects of age, sex, and disease severity on the incubation period were expiated by using multivariate logistic regression model with interval censoring. RESULTS: The mean incubation period of the Delta variant was estimated at 6.64 days (95% credible interval: 6.27-7.00). We found that female cases and cases with severe symptoms had relatively longer mean incubation periods than male cases and those with nonsevere symptoms, respectively. One-day increase in the incubation period of Delta variants was associated with a weak decrease in the probability of having severe illness with an adjusted odds ratio of 0.88 (95% credible interval: 0.71-1.07). CONCLUSIONS: In this study, the incubation period was found to vary across different levels of sex, age, and disease severity of COVID-19. These findings provide additional information on the incubation period of Delta variants and highlight the importance of continuing surveillance and monitoring of the epidemiological characteristics of emerging SARS-CoV-2 variants as they evolve.


Тема - темы
COVID-19 , SARS-CoV-2 , Female , Humans , Male , COVID-19/epidemiology , Infectious Disease Incubation Period , Likelihood Functions , SARS-CoV-2/genetics , Retrospective Studies
14.
Tohoku J Exp Med ; 258(4): 327-332, 2022 Nov 23.
Статья в английский | MEDLINE | ID: covidwho-2109461

Реферат

Antithrombin deficiency is a high-risk factor for venous thromboembolism during pregnancy, whereas cerebral venous thrombosis is rare. Cerebral venous thrombosis related to coronavirus disease 2019 (COVID-19) vaccines has been reported; however, there are a few reports of cerebral venous thrombosis after a messenger RNA (mRNA) vaccination. A 25-year-old female in her sixth week of pregnancy presented with headache 24 days after BNT162b2 mRNA COVID-19 vaccination. The following day, she presented with altered sensorium and was diagnosed with severe cerebral venous thrombosis. She demonstrated heparin resistance and was found to have an inherited antithrombin deficiency. A heterozygous missense variant in SERPINC1 (c.379T>C, p.Cys127Arg, 'AT Morioka') was detected by DNA analysis. Despite intensive care with unfractionated heparin, antithrombin concentrate, and repeated endovascular treatments, she died on the sixth day of hospitalization. Cerebral venous thrombosis in pregnant women with an antithrombin deficiency can follow a rapid and fatal course. Treatment with unfractionated heparin and antithrombin concentrate may be ineffective in severe cerebral venous thrombosis cases with antithrombin deficiency. Early recognition of antithrombin deficiency and an immediate switch to other anticoagulants may be required. Although the association between cerebral venous thrombosis and the vaccine is uncertain, COVID-19 vaccinations may require careful evaluation for patients with prothrombic factors.


Тема - темы
Antithrombin III Deficiency , COVID-19 , Venous Thrombosis , Humans , Female , Pregnancy , Adult , Pregnant Women , COVID-19/complications , COVID-19 Vaccines/adverse effects , BNT162 Vaccine , Heparin , RNA, Messenger , Antithrombin III Deficiency/complications , Antithrombin III Deficiency/genetics , Antithrombins/therapeutic use , Anticoagulants , Venous Thrombosis/etiology , Vaccination/adverse effects
15.
Epidemiol Serv Saude ; 31(1): e2021836, 2022.
Статья в английский, португальский | MEDLINE | ID: covidwho-2109459

Реферат

OBJECTIVE: To describe the profile and temporal variation of hospital admissions and deaths due to severe acute respiratory syndrome (SARS) caused by COVID-19 in Piauí, Brazil, according to place of hospitalization. METHODS: We performed a descriptive study using data from the Influenza Surveillance Information System between 2020 and 2021. Case fatality ratio among hospital records with outcome and respective 95% confidence intervals (95%CI) were calculated. RESULTS: We included 12,649 individuals who were mostly male (57.1%), Black (61.2%) and had one or two comorbidities (30.5%). Case fatality ratio among hospital records with outcome was higher in the state's interior region than in its capital, with proportion of 44.1% (95%CI 42.0;46.3) for those who were hospitalized, 82.3% (95%CI 79.7;84.8) for those admitted to intensive care units and 96.6% (95%CI 94.9;97.8) for those undergoing invasive mechanical ventilation. CONCLUSION: The study enabled characterization of the profile of SARS hospitalizations due to COVID-19 in Piauí and demonstrated high case fatality ratio, among hospital records with outcome, which remained high during the study period, especially in the interior of the state.


Тема - темы
COVID-19 , Influenza, Human , Brazil/epidemiology , COVID-19/epidemiology , Female , Hospitalization , Hospitals , Humans , Influenza, Human/epidemiology , Male
16.
Rev Lat Am Enfermagem ; 30(spe): e3744, 2022.
Статья в английский, португальский, испанский | MEDLINE | ID: covidwho-2109437

Реферат

OBJECTIVE: to estimate the prevalence of emotional and behavioral problems in adolescents in the context of the COVID-19 pandemic e to explore adolescents' perception of emotional and behavioral problems identified. METHOD: mixed-method explanatory sequential design. Participants were 479 adolescents aged 15 to 18 from a Brazilian Central-West region capital. RESULTS: with a total of 479 participants, mean age was 16.03 years (SD=1.01). The prevalence of emotional and behavioral problems was 61.17%, and there was a difference between the sexes (ORb=2.93; p<0.01). The highest prevalence was related to peer relationship problems (54.49%) and emotional symptoms (52.40%). Adolescents noticed an increase in loneliness, anxiety, sadness, distancing from friends and difficulties in socializing during the pandemic. CONCLUSION: most of the investigated adolescents were classified as having emotional and behavioral problems, and girls were more likely to have them than boys. The adolescents' statements reinforce the quantitative findings. In this way, there is a need to implement actions to promote and restore the adolescents' mental health, in order to mitigate the COVID-19 pandemic socio-emotional impact on this population. KEYPOINTS: (1) The COVID-19 pandemic had a negative impact on emotions and behaviors. (2) 61.17% of adolescents were classified as having emotional and behavioral problems (EBPs). (3) Girls presented the highest level of prevalence of EBP in the pandemic context. (4) Peer relationship problems and emotional symptoms were the most prevalent.


Тема - темы
Adolescent Behavior , COVID-19 , Problem Behavior , Male , Female , Adolescent , Humans , Problem Behavior/psychology , Pandemics , Adolescent Behavior/psychology , Cross-Sectional Studies , Emotions
17.
PLoS One ; 17(11): e0277470, 2022.
Статья в английский | MEDLINE | ID: covidwho-2109335

Реферат

INTRODUCTION: The World Health Organization recognizes dementia as a public health priority and highlights research as an action to respond to the consequences, with early career dementia researchers (ECDRs) representing the key driving force. Due to the COVID-19 pandemic, however, biomedical and psychosocial dementia research was strained worldwide. The aim of this study was to understand the impact of the pandemic on ECDRs. METHODS: In autumn 2021, the Alzheimer's Association International Society to Advance Alzheimer's Research and Treatment (ISTAART) Professional Interest Area to Elevate Early Career Researchers (PEERs) and University College London conducted an online survey querying ECDRs' experiences during the COVID-19 pandemic. The survey was shared through the ISTAART network, social media, podcasts, and emailing lists. Data were analyzed using descriptive and inferential statistics. RESULTS: Survey data from n = 321 ECDRs from 34 countries were analyzed (67.6% women; 78.8% working in academia). Overall, 77.8% of ECDRs surveyed indicated research delays, 53.9% made project adjustments, 37.9% required additional or extended funding, and 41.8% reported a negative impact on career progression. Moreover, 19.9% felt unsupported by their institutions and employers (33% felt well supported, 42.7% somewhat supported). ECDR's conference attendance remained the same (26.5%) or increased (More: 28.6%; a lot more: 5.6%) since the start of the pandemic. Continental differences were visible, while the impact of the pandemic did not differ greatly based on ECDRs' sociodemographic characteristics. CONCLUSIONS: The COVID-19 pandemic had a substantial impact on ECDRs worldwide and institutions, employers, and funding bodies are urged to consider the implications and lessons-learned when working with, managing, and promoting ECDRs. Strategies related to the pandemic and general career support to improve ECDRs career progression are discussed, including social media training, digital networking, and benefits of hybrid events. Global resources specific for ECDRs are highlighted.


Тема - темы
Alzheimer Disease , COVID-19 , Social Media , Humans , Female , Male , Pandemics , COVID-19/epidemiology , Research Personnel
18.
PLoS One ; 17(11): e0277435, 2022.
Статья в английский | MEDLINE | ID: covidwho-2109334

Реферат

Coronavirus disease 2019 (COVID-19) vaccination of adolescent and young adults is important for infection control. Factors influencing vaccination behavior in this age group include the source of information about the vaccine and social norms. However, there are few studies on factors influencing vaccination behavior among Japanese university students. This study aimed to assess beliefs, attitudes, and sources of information about the COVID-19 vaccine among university students in Japan. A cross-sectional online questionnaire survey was conducted among students in Teikyo University, Japan in September, 2021. The survey was designed to collect demographic information, vaccination status, attitudes, beliefs, and anxiety about the vaccine, sources of information, and whether or not the participant watched an educational movie. The factors associated with beliefs and attitudes were analyzed using logistic and linear regression. A total of 4,062 valid questionnaires were retrieved. The positive vaccine behavior group included 3,725 students (91.7%). The most common source of information on the COVID-19 vaccine was TV/radio (75.0%), and the most common Social networking service (SNS) for COVID-19 information was Twitter (31.1%). Approximately 85% students believed in the efficacy of vaccination. Positive attitude was associated with female sex and watching an educational movie by the university. Concern about the vaccine was positively associated with information from acquaintances or Instagram, and negatively associated with information from Twitter, and watching the educational movie. The majority of students had positive beliefs and attitudes toward COVID-19 vaccination, and social media and educational movies produced by the university had a large influence on their attitude toward vaccination behavior. On the contrary, some students were anxious about vaccination. Promotion of educational movies on social media by the universities is an effective way to encourage vaccination among young people.


Тема - темы
COVID-19 , Vaccines , Young Adult , Adolescent , Humans , Female , Universities , COVID-19/epidemiology , COVID-19/prevention & control , COVID-19 Vaccines , Japan/epidemiology , Cross-Sectional Studies , Health Knowledge, Attitudes, Practice , Vaccination , Students , Surveys and Questionnaires
19.
PLoS One ; 17(11): e0277301, 2022.
Статья в английский | MEDLINE | ID: covidwho-2109330

Реферат

PURPOSE: To assess hospitalized COVID-19 inpatients for the prevalence of retinopathy and tear film SARS-CoV-2 RNA, and associated risk factors for their detection. METHODS: Hospitalized COVID-19 patients underwent dilated ophthalmic examination and fundus photography. Conjunctival swabs were assessed for SARS-CoV-2 RT-PCR via a triple target assay. We assessed the relationships of retinopathy with clinical outcomes, systemic risk factors and laboratory data. RESULTS: The median age was 59.5 years and 29 (48%) were female. Retinopathy associated with COVID-19 was observed in 12 of 60 patients (20%). The median age of patients with COVID-19 retinopathy was 51.5 compared to 62.5 years in individuals without retinopathy (p = 0.01). Median BMI was 34.3 in patients with retinopathy versus 30.9 in those without retinopathy (p = 0.04). Fifteen of 60 patients (25%) tested SARS-CoV-2 RNA-positive in their tear film without a relationship with timing of illness and hospitalization. The N2 gene was particularly sensitive with 18 of 19 eyes (94.7%) showing N2-positivity, including 2 patients with alpha variant-positivity (B.1.1.7). CONCLUSION: Retinopathy was observed in 20% of patients hospitalized for COVID-19. Patients with retinopathy were more likely to be younger and have higher BMI than hospitalized patients without retinopathy. Tear film SARS-CoV-2 RNA was detected in 25% of patients. The relationship of obesity and age with retinopathy requires further investigation.


Тема - темы
COVID-19 , Retinal Diseases , Humans , Female , Middle Aged , Male , COVID-19/diagnosis , SARS-CoV-2/genetics , RNA, Viral/genetics , RNA, Viral/analysis , Reverse Transcriptase Polymerase Chain Reaction , Risk Factors
20.
PLoS One ; 17(11): e0275832, 2022.
Статья в английский | MEDLINE | ID: covidwho-2109322

Реферат

BACKGROUND: Studies from Asia, Europe and the USA indicate that widely available haematological parameters could be used to determine the clinical severity of Coronavirus disease 2019 (COVID-19) and predict management outcome. There is limited data from Africa on their usefulness in patients admitted to Intensive Care Units (ICUs). We performed an evaluation of baseline haematological parameters as prognostic biomarkers in ICU COVID-19 patients. METHODS: Demographic, clinical and laboratory data were collected prospectively on patients with confirmed COVID-19, admitted to the adult ICU in a tertiary hospital in Cape Town, South Africa, between March 2020 and February 2021. Robust Poisson regression methods and receiver operating characteristic (ROC) curves were used to explore the association of haematological parameters with COVID-19 severity and mortality. RESULTS: A total of 490 patients (median age 54.1 years) were included, of whom 237 (48%) were female. The median duration of ICU stay was 6 days and 309/490 (63%) patients died. Raised neutrophil count and neutrophil/lymphocyte ratio (NLR) were associated with worse outcome. Independent risk factors associated with mortality were age (ARR 1.01, 95%CI 1.0-1.02; p = 0.002); female sex (ARR 1.23, 95%CI 1.05-1.42; p = 0.008) and D-dimer levels (ARR 1.01, 95%CI 1.002-1.03; p = 0.016). CONCLUSIONS: Our study showed that raised neutrophil count, NLR and D-dimer at the time of ICU admission were associated with higher mortality. Contrary to what has previously been reported, our study revealed females admitted to the ICU had a higher risk of mortality.


Тема - темы
COVID-19 , Adult , Humans , Female , Middle Aged , Male , COVID-19/epidemiology , Tertiary Care Centers , South Africa/epidemiology , Intensive Care Units , Hospitalization , Retrospective Studies
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