THE MECHANISM OF BLOOD COAGULATION IN COVID-19 PATHOGENESIS

ABSTRACT

One of the formidable complications of SARS-COV-2 infection leading to death is coagulopathy. The mechanisms of the development of this pathology at the present stage have not been studied, and clinical blood tests indicate that against the background of normal blood clotting indices, only the Ddi-D-dimer protein exceeds the norm many times over. The aim of the study was to study and analyze biochemical parameters in patients of Primorsky Region (Russia) infected with SARS-COV-2 against the background of concomitant vascular pathology and the development of DIC syndrome. The authors came to the conclusion about the existence of two mechanisms of circulatory disorders in the vessels of the microvasculature, associated with the violation of the integrity of the vascular wall and destruction of erythrocytes. Further research is needed to study the mechanisms of SARS-CoV-2 aggression, leading to thrombotic complications.