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Efficacy of hand hygiene products against SARS COV-2
Antimicrobial Resistance and Infection Control ; 10(SUPPL 1), 2021.
Article in English | EMBASE | ID: covidwho-1448396
ABSTRACT

Introduction:

Hand hygiene is the primary measure in preventing transmission of pathogens to patients and healthcare workers. With more than 150 million reported COVID-19 cases worldwide of which many require hospital care, it is vital that essential hand hygiene products are sufficiently efficacious against SARS-CoV-2.

Objectives:

Microbicidal actives (e.g. ethanol) have been shown to be efficacious against other coronaviruses. The objective of this study is to demonstrate viricidal activity of a range of formulated skin care products against SARS-CoV-2 specifically.

Methods:

Testing was conducted using ASTM E1052-20 and EN144762013 + A22019 test methods. The test product was challenged with an aliquot of viral inoculum as well as an interference substance (for EN14476) then held for an exposure (contact) time. Immediately after the contact time, the reaction mixture was neutralized. The neutralized sample was assayed for infectious virus via a cell culture-based viral infectivity assay (TCID50 assay). The results were compared to a mock-treated Virus Recovery Control to determine the virucidal activity ( Log10 reduction) by the test product.

Results:

Table I shows activity against SARS-CoV-2 following exposure to 4 products according to EN14476 and 1 product according to E1052.

Conclusion:

Alcohol-based sanitizers are effective against SARSCoV- 2. This effectiveness is not strongly affected either by product format or by alcohol composition if a sufficient concentration is applied. SCJ Professional BZK based hand sanitizer and Hydrogen Peroxide/ Phenoxyethanol based antimicrobial foam soap are also both effective against SARS-CoV-2. As a result, we would recommend the use of product formulations meeting those specifications in health care, community, and home environments as part of hand hygiene practices to control the transmission of COVID-19.

Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Antimicrobial Resistance and Infection Control Year: 2021 Document Type: Article

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Full text: Available Collection: Databases of international organizations Database: EMBASE Language: English Journal: Antimicrobial Resistance and Infection Control Year: 2021 Document Type: Article