Antimicrobial Activity in the Gasphase with Hypochloric Acid
Current Directions in Biomedical Engineering
; 7(2):511-514, 2021.
Article
in English
| Scopus | ID: covidwho-1590049
ABSTRACT
Background:
The study investigated if the disinfecting potential of Hypochlorous acid (HOCl) in suspensions are transferrable to in-air cleaning applications and to what extent aerosolized HOCl solutions can deactivate indoor microbial contaminations in-air at or below legal limits. Material andMethod:
For the liquid disinfection we used a standard suspension disinfection test protocol. For the in-air tests we conducted several experiments where aerosolized bacterial suspensions were injected into lab chambers preloaded with different HOCl gas concentrations.Results:
In suspension experiments we found sufficient efficacies for all studied organisms at minimum concentrations of 200 ppm HOCl. The in-air measurement set-up allows to follow microbe deactivation by HOCl interaction. The deactivation rate increases with the HOCl concentration, and the values are highest for Gram-negative bacteria.Conclusion:
We confirmed our hypothesis of the high disinfecting power of HOCl in-air at safe levels for populated indoor places. The investigated bacteria provide a model system for infectious particles, including enveloped viruses (to which Coronavirus belongs). These early results suggest that HOCl should be further evaluated as an air-cleaning method which may complement established concepts. © 2021 by Walter de Gruyter Berlin/Boston.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
English
Journal:
Current Directions in Biomedical Engineering
Year:
2021
Document Type:
Article
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