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Two Cases of Miliary and Disseminated Coccidioidomycosis Following Glucocorticoid Therapy and Literature Review.
Sous, Rowis; Levkiavska, Yuliya; Sharma, Rupam; Jariwal, Roopam; Amodio, Daniela; Johnson, Royce H; Heidari, Arash; Kuran, Rasha.
  • Sous R; Kern Medical, Bakersfield, CA, USA.
  • Levkiavska Y; Kern Medical, Bakersfield, CA, USA.
  • Sharma R; Kern Medical, Bakersfield, CA, USA.
  • Jariwal R; Valley Fever Institute at Kern Medical, Bakersfield, CA, USA.
  • Amodio D; Kern Medical, Bakersfield, CA, USA.
  • Johnson RH; Rio Bravo Family Medicine Residency Program, Bakersfield, CA, USA.
  • Heidari A; Kern Medical, Bakersfield, CA, USA.
  • Kuran R; Valley Fever Institute at Kern Medical, Bakersfield, CA, USA.
J Investig Med High Impact Case Rep ; 10: 23247096211051928, 2022.
Article in English | MEDLINE | ID: covidwho-1714632
ABSTRACT
A 49-year-old man with no significant past medical history received dexamethasone as part of his treatment for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Less than 3 weeks later, the patient developed acute respiratory distress syndrome. Radiological and serological testing led to a diagnosis of acute hypoxic miliary coccidioidomycosis. A 52-year-old man with a past medical history of chronic kidney disease (CKD) was treated with prednisone for focal segmental glomerulosclerosis (FSGS). Within 2 weeks, this patient developed bilateral lower extremity weakness. Radiology, serology, and lumbar puncture proved a diagnosis of reactivated coccidioidomycosis with miliary pattern and coccidioidomycosis meningoencephalitis with arachnoiditis. Whether treatment with glucocorticoids caused reactivation of coccidioidomycosis is discussed in this case series.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Coccidioidomycosis / COVID-19 Drug Treatment Type of study: Case report / Diagnostic study / Prognostic study / Reviews Limits: Humans / Male / Middle aged Language: English Journal: J Investig Med High Impact Case Rep Year: 2022 Document Type: Article Affiliation country: 23247096211051928

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Respiratory Distress Syndrome / Coccidioidomycosis / COVID-19 Drug Treatment Type of study: Case report / Diagnostic study / Prognostic study / Reviews Limits: Humans / Male / Middle aged Language: English Journal: J Investig Med High Impact Case Rep Year: 2022 Document Type: Article Affiliation country: 23247096211051928