Your browser doesn't support javascript.
Clinically mild encephalitis/encephalopathy with a reversible splenial lesion of the corpus callosum in childhood: a single-center experience
Turkish Journal of Medical Sciences ; 52(2):405-412, 2022.
Article in English | EMBASE | ID: covidwho-1855908
ABSTRACT
Background/

aim:

Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinicoradiological syndrome that typically presents with central nervous system symptoms such as loss of consciousness, seizure, headache, and ophthalmoparesis. Materials and

methods:

Here, we highlight the characteristics of this syndrome together with the clinical and MRI findings of 6 pediatric patients with MERS.

Results:

Between January 2017 and October 2020, 6 patients with MERS (3 boys and 3 girls) presented to our center. The mean age was 122 ± 54.6 (min-max 44-180) months. None of the patients had a chronic disease. In our study, infectious agents were detected in 4 patients (66.6%), while noninfectious causes (one seizure and the other hyponatremia) were detected in two patients. All of our cases were discharged without any sequelae after an average of 12.1 ± 7 (min–max 4–20) days of hospitalization. In 1 patient (case 6), control MRI could not be performed, and the radiological recovery of our other patients was shown to be between 14 days and 2 months.

Conclusion:

MERS is an acute encephalopathy with good prognosis and should be considered by neurologists in differential diagnosis due to its variable clinical presentation and specific MRI findings.
Keywords
aciclovir; alanine aminotransferase; aspartate aminotransferase; C reactive protein; ceftriaxone; doxycycline; Epstein Barr virus antigen; glucose; hemoglobin; immunoglobulin; immunoglobulin G; immunoglobulin M; methylprednisolone; sodium; abdominal pain; acute appendicitis; acute brain disease; adolescent; alanine aminotransferase blood level; apparent diffusion coefficient; article; aspartate aminotransferase blood level; ataxic gait; blood pressure; brain disease; breathing rate; case report; cerebrospinal fluid; child; chronic disease; clinical article; consciousness disorder; contrast enhancement; coronavirus disease 2019; corpus callosum; Coxiella burnetii; dentate nucleus; diarrhea; differential diagnosis; diffusion weighted imaging; diplopia; echocardiography; electroencephalography; encephalitis; Epstein Barr virus; eye examination; eye fundus; female; fever; fluid-attenuated inversion recovery imaging; follow up; glucose blood level; headache; hemoglobin blood level; human; hypersomnia; hyponatremia; leukocyte count; lumbar puncture; male; meningoencephalitis; middle cerebellar peduncle; myocarditis; nasopharyngeal swab; nuclear magnetic resonance imaging; ophthalmoplegia; oxygen saturation; pediatric multisystem inflammatory syndrome; physical examination; platelet count; polymerase chain reaction; preschool child; Q fever; real time polymerase chain reaction; school child; seizure; sodium blood level; somnolence; strabismus; T1 weighted imaging; T2 weighted imaging; tonic clonic seizure; ultrasound; upper respiratory tract infection; vomiting

Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Observational study / Prognostic study Topics: Long Covid Language: English Journal: Turkish Journal of Medical Sciences Year: 2022 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: Databases of international organizations Database: EMBASE Type of study: Observational study / Prognostic study Topics: Long Covid Language: English Journal: Turkish Journal of Medical Sciences Year: 2022 Document Type: Article