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Mechanisms of SARS-CoV-2 Infection-Induced Kidney Injury: A Literature Review.
He, Weihang; Liu, Xiaoqiang; Hu, Bing; Li, Dongshui; Chen, Luyao; Li, Yu; Tu, Yechao; Xiong, Situ; Wang, Gongxian; Deng, Jun; Fu, Bin.
  • He W; Reproductive Medicine Center, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Liu X; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Hu B; Jiangxi Institute of Urology, Nanchang, China.
  • Li D; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Chen L; Reproductive Medicine Center, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Li Y; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Tu Y; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Xiong S; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Wang G; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Deng J; Department of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
  • Fu B; Jiangxi Institute of Urology, Nanchang, China.
Front Cell Infect Microbiol ; 12: 838213, 2022.
Article in English | MEDLINE | ID: covidwho-1924077
ABSTRACT
The severe acute respiratory coronavirus 2 (SARS-CoV-2) has become a life-threatening pandemic. Clinical evidence suggests that kidney involvement is common and might lead to mild proteinuria and even advanced acute kidney injury (AKI). Moreover, AKI caused by coronavirus disease 2019 (COVID-19) has been reported in several countries and regions, resulting in high patient mortality. COVID-19-induced kidney injury is affected by several factors including direct kidney injury mediated by the combination of virus and angiotensin-converting enzyme 2, immune response dysregulation, cytokine storm driven by SARS-CoV-2 infection, organ interactions, hypercoagulable state, and endothelial dysfunction. In this review, we summarized the mechanism of AKI caused by SARS-CoV-2 infection through literature search and analysis.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acute Kidney Injury / COVID-19 Type of study: Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Journal: Front Cell Infect Microbiol Year: 2022 Document Type: Article Affiliation country: Fcimb.2022.838213

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Acute Kidney Injury / COVID-19 Type of study: Prognostic study / Reviews Topics: Long Covid Limits: Humans Language: English Journal: Front Cell Infect Microbiol Year: 2022 Document Type: Article Affiliation country: Fcimb.2022.838213