Your browser doesn't support javascript.
Heart rate variability and adrenal size provide clues to sudden cardiac death in hospitalized COVID-19 patients.
Ranard, Benjamin L; Megjhani, Murad; Terilli, Kalijah; Yarmohammadi, Hirad; Ausiello, John; Park, Soojin.
  • Ranard BL; Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, United States of America.
  • Megjhani M; Program for Hospital and Intensive Care Informatics, Departments of Neurology and Biomedical Informatics, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, United States of America.
  • Terilli K; Program for Hospital and Intensive Care Informatics, Departments of Neurology and Biomedical Informatics, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, United States of America.
  • Yarmohammadi H; Division of Cardiology, Department of Medicine, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, United States of America.
  • Ausiello J; Division of Endocrinology, Department of Medicine, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, United States of America.
  • Park S; Program for Hospital and Intensive Care Informatics, Departments of Neurology and Biomedical Informatics, NewYork-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, United States of America. Electronic address: sp3291@cumc.columbia.edu.
J Crit Care ; 71: 154114, 2022 10.
Article in English | MEDLINE | ID: covidwho-1936752
ABSTRACT

PURPOSE:

To examine the association between a measure of heart rate variability and sudden cardiac death (SCD) in COVID-19 patients.

METHODS:

Patients with SARS-COV-2 infection admitted to Columbia University Irving Medical Center who died between 4/25/2020 and 7/14/2020 and had an autopsy were examined for root mean square of successive differences (RMSSD), organ weights, and evidence of SCD.

RESULTS:

Thirty COVID-19 patients were included and 12 had SCD. The RMSSD over 7 days without vs with SCD was median 0.0129 (IQR 0.0074-0.026) versus 0.0098 (IQR 0.0056-0.0197), p < 0.0001. The total adjusted adrenal weight of the non-SCD group was 0.40 g/kg (IQR 0.35-0.55) versus 0.25 g/kg (IQR 0.21-0.31) in the SCD group, p = 0.0007.

CONCLUSIONS:

Hospitalized patients with COVID-19 who experienced SCD had lower parasympathetic activity (RMSSD) and smaller sized adrenal glands. Further research is required to replicate these findings.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: J Crit Care Journal subject: Critical Care Year: 2022 Document Type: Article Affiliation country: J.jcrc.2022.154114

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Type of study: Observational study / Prognostic study Limits: Humans Language: English Journal: J Crit Care Journal subject: Critical Care Year: 2022 Document Type: Article Affiliation country: J.jcrc.2022.154114