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Association of Functional Characteristics and Physiotherapy with COVID-19 Mortality in Intensive Care Unit in Inpatients with Cardiovascular Diseases.
Silva, Chiara Andrade; Lopes, Agnaldo José; Papathanasiou, Jannis; Reis, Luis Felipe Fonseca; Ferreira, Arthur Sá.
  • Silva CA; Postgraduate Program of Rehabilitation Sciences, Centro Universitário Augusto Motta/UNISUAM, Rio de Janeiro 20080-003, Brazil.
  • Lopes AJ; Postgraduate Program of Rehabilitation Sciences, Centro Universitário Augusto Motta/UNISUAM, Rio de Janeiro 20080-003, Brazil.
  • Papathanasiou J; Department of Medical Imaging, Allergology & Physiotherapy, Faculty of Dental Medicine, Medical University of Plovdiv, 4002 Plovdiv, Bulgaria.
  • Reis LFF; Department of Kinesitherapy, Faculty of Public Health "Prof. Dr. Tzecomir Vodenicharov, DSc.", Medical University of Sofia, 1431 Sofia, Bulgaria.
  • Ferreira AS; Postgraduate Program of Rehabilitation Sciences, Centro Universitário Augusto Motta/UNISUAM, Rio de Janeiro 20080-003, Brazil.
Medicina (Kaunas) ; 58(6)2022 Jun 18.
Article in English | MEDLINE | ID: covidwho-1964024
ABSTRACT
Background and

Objectives:

To estimate the association between admission functional outcomes and exposure to physiotherapy interventions with mortality rate in intensive care unit (ICU) inpatients with cardiovascular diseases and new coronavirus disease (COVID-19). Materials and

Methods:

Retrospective cohort including 100 ICU inpatients (mean (standard deviation), age 75 (16) years) split into COVID-19+ or COVID-19-. The association of in-ICU death with admission functional outcomes and physiotherapy interventions was investigated using univariable and multivariable regression models.

Results:

In total, 42 (42%) patients tested positive for COVID-19. In-ICU mortality rate was 37%, being higher for the COVID-19+ group (odds ratio, OR (95% CI) 3.15 (1.37-7.47), p = 0.008). In-ICU death was associated with lower admission ICU Mobility Scale score (0.81 (0.71-0.91), p = 0.001). Restricted mobility (24.90 (6.77-161.94), p < 0.001) and passive kinesiotherapy (30.67 (9.49-139.52), p < 0.001) were associated with in-ICU death, whereas active kinesiotherapy (0.13 (0.05-0.32), p < 0.001), standing (0.12 (0.05-0.30), p < 0.001), or walking (0.10 (0.03-0.27), p < 0.001) were associated with in-ICU discharge.

Conclusions:

In-ICU mortality was higher for inpatients with cardiovascular diseases who had COVID-19+, were exposed to invasive mechanical ventilation, or presented with low admission mobility scores. Restricted mobility or passive kinesiotherapy were associated with in-ICU death, whereas active mobilizations (kinesiotherapy, standing, or walking) were associated with in-ICU discharge in this population.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Aged / Humans Language: English Journal subject: Medicine Year: 2022 Document Type: Article Affiliation country: Medicina58060823

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Cardiovascular Diseases / COVID-19 Type of study: Cohort study / Observational study / Prognostic study Limits: Aged / Humans Language: English Journal subject: Medicine Year: 2022 Document Type: Article Affiliation country: Medicina58060823