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COVID-19 vaccines in pregnancy.
Nunes, Marta C; Madhi, Shabir A.
  • Nunes MC; South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
  • Madhi SA; South African Medical Research Council, Vaccines and Infectious Diseases Analytics Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; Department of Science and Technology/National Research Foundation South African Research Chair Initiative in Vaccine Preventable Diseases, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa; African Leadership in Vaccinology Expertise, Faculty of Health Sciences, University o
Trends Mol Med ; 28(8): 662-680, 2022 08.
Article in English | MEDLINE | ID: covidwho-2233879
ABSTRACT
COVID-19 caused by SARS-CoV-2 coronavirus has been associated with severe illness in pregnant women. Furthermore, COVID-19 during pregnancy is associated with adverse fetal outcomes including preterm labor. Pregnant women were largely excluded from initial clinical trials investigating the safety and efficacy of COVID-19 vaccines; however, they have since been included as part of the routine roll-out of these vaccines. This narrative review synthesizes the evidence on the safety, immunogenicity, and effectiveness predominantly of the mRNA COVID-19 vaccines which have been most widely used in pregnant women.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / COVID-19 Vaccines / COVID-19 Type of study: Prognostic study / Reviews Topics: Vaccines Limits: Female / Humans / Infant, Newborn / Pregnancy Language: English Journal: Trends Mol Med Journal subject: Molecular Biology Year: 2022 Document Type: Article Affiliation country: J.molmed.2022.04.012

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pregnancy Complications, Infectious / COVID-19 Vaccines / COVID-19 Type of study: Prognostic study / Reviews Topics: Vaccines Limits: Female / Humans / Infant, Newborn / Pregnancy Language: English Journal: Trends Mol Med Journal subject: Molecular Biology Year: 2022 Document Type: Article Affiliation country: J.molmed.2022.04.012