COVID-19 in the Immunocompromised Host, Including People with Human Immunodeficiency Virus.

Jakharia, Niyati; Subramanian, Aruna K; Shapiro, Adrienne E

Jakharia, Niyati; Subramanian, Aruna K; Shapiro, Adrienne E.

Jakharia N; Department of Medicine, Division of Infectious Disease, Stanford University School of Medicine, 300 Pasteur Drive, Lane L134, Stanford, CA 94305, USA. Electronic address: nnarsana@stanford.edu.
Subramanian AK; Department of Medicine, Division of Infectious Disease, Stanford University School of Medicine, 300 Pasteur Drive, Lane L134, Stanford, CA 94305, USA.
Shapiro AE; Department of Global Health, University of Washington, 325 Ninth Avenue, Box 359927, Seattle, WA 98104, USA; Department of Medicine, Division of Allergy and Infectious Diseases, University of Washington, Seattle, WA, USA.

Infect Dis Clin North Am ; 36(2): 397-421, 2022 06.

Article in English | MEDLINE | ID: covidwho-2130983

ABSTRACT

ABSTRACT

This review describes the incidence, epidemiology, and risk factors for mortality of COVID-19 in immunocompromised patients, including persons with human immunodeficiency virus. It describes various preventive measures, including vaccines and their effectiveness and the role of monoclonal antibodies for pre-exposure prophylaxis. It also reviews the different treatment options for immunocompromised individuals, including antivirals, monoclonal antibodies, and immunomodulators. Lastly, it describes the impact of COVID-19 on transplantation and continuity care of this population.

Subject(s)

COVID-19; HIV Infections; Antibodies, Monoclonal; HIV; HIV Infections/complications; HIV Infections/epidemiology; Humans; Immunocompromised Host

Keywords

CD4; COVID-19; HIV; Hematopoietic stem cell transplant; Immunocompromise; Immunosuppression; SARS-CoV-2; Solid organ transplant

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Full text: Available Collection: International databases Database: MEDLINE Main subject: HIV Infections / COVID-19 Type of study: Observational study / Prognostic study Topics: Long Covid / Vaccines Limits: Humans Language: English Journal: Infect Dis Clin North Am Journal subject: Communicable Diseases Year: 2022 Document Type: Article

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