Cardiometabolic and psychocognitive features of the post-COVID period in patients with atrial fibrillation
Profilakticheskaya Meditsina
; 26(4):43-50, 2023.
Article
in Russian
| EMBASE | ID: covidwho-2326459
ABSTRACT
The number of people with long-term consequences of COVID-19 is increasing worldwide. The long-term prognosis for patients remains poorly understood. Objective. To study cardiometabolic and psychocognitive features in comorbid elderly patients with atrial fibrillation (AF), de-pending on the presence of post-COVID syndrome (PCS). Material and methods. The observational analytical cohort study included 223 patients with AF and comorbidity (coronary artery disease, hypertension, obesity, type 2 diabetes mellitus) aged 60-74, who were divided into two groups group 1 included 123 patients without COVID-19 and group 2 included 110 patients with a history of COVID-19 and the presence of PCS. The study evaluated laboratory and instrumental tests, and a general clinical study assessing psychocognitive disorders using the SPMSQ and HADS questionnaires was conducted. Results and discussion. In COVID-19 survivors, compared with patients of group 1, there were more pronounced atherogenic changes in total cholesterol (TC) (p=0.003), low-density lipoprotein cholesterol (p<0.001), and triglycerides (p=0.011). Lower dia-stolic blood pressure was found in COVID-19 survivors (p<0.001). In addition, patients in group 2 had higher median pulse pressure (p<0.001) and heart rate (p<0.001). In group 2 patients, a larger ascending aorta diameter was observed (p<0.001). The anx-iety-depressive syndrome was more common in COVID-19 survivors with comorbidities, and a statistically significant difference was found in clinical anxiety (24%, p=0.041) and subclinical depression (21%, p=0.015). When assessing cognitive function, mod-erate cognitive impairment was detected in 22% (p=0.005) of patients with PCS and severe cognitive impairment in 2% (p=0.007). Conclusion. In comorbid elderly patients with the post-COVID syndrome, a high prevalence of psychocognitive disorders and adverse cardiometabolic changes were observed, supporting the need for long-term monitoring of the general clinical condition and psychocognitive status of COVID-19 survivors.Copyright © 2023, Media Sphera Publishing Group. All rights reserved.
anxiety; atrial fibrillation; cognitive impairment; comorbidity; coronary heart disease; covid-19; depression; diabetes; hypertension; obesity; old age; post-COVID syndrome; psychosomatic disorders; SARS-CoV-2; adult; aged; aortic diameter; article; ascending aorta; blood pressure; cholesterol blood level; clinical assessment; cognition; cognitive defect; cohort analysis; controlled study; coronary artery disease; coronavirus disease 2019; diabetes mellitus; female; heart rate; Hospital Anxiety and Depression Scale; human; ischemic heart disease; long COVID; major clinical study; male; middle aged; non insulin dependent diabetes mellitus; nonhuman; prevalence; psychosomatic disorder; pulse pressure; questionnaire; Severe acute respiratory syndrome coronavirus 2; Short Portable Mental Status Questionnaire; subsyndromal depression; survivor; low density lipoprotein cholesterol; triacylglycerol
Full text:
Available
Collection:
Databases of international organizations
Database:
EMBASE
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Language:
Russian
Journal:
Profilakticheskaya Meditsina
Year:
2023
Document Type:
Article
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