Cardiac and arrhythmic complications in patients with COVID-19.
J Cardiovasc Electrophysiol
; 31(5): 1003-1008, 2020 05.
Article
in English
| MEDLINE | ID: covidwho-258908
ABSTRACT
In December 2019, the world started to face a new pandemic situation, the severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2). Although coronavirus disease (COVID-19) clinical manifestations are mainly respiratory, major cardiac complications are being reported. Cardiac manifestations etiology seems to be multifactorial, comprising direct viral myocardial damage, hypoxia, hypotension, enhanced inflammatory status, ACE2-receptors downregulation, drug toxicity, endogenous catecholamine adrenergic status, among others. Studies evaluating patients with COVID-19 presenting cardiac injury markers show that it is associated with poorer outcomes, and arrhythmic events are not uncommon. Besides, drugs currently used to treat the COVID-19 are known to prolong the QT interval and can have a proarrhythmic propensity. This review focus on COVID-19 cardiac and arrhythmic manifestations and, in parallel, makes an appraisal of other virus epidemics as SARS-CoV, Middle East respiratory syndrome coronavirus, and H1N1 influenza.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Arrhythmias, Cardiac
/
Coronavirus Infections
/
Coronavirus
/
Cardiomyopathies
/
Myocarditis
Type of study:
Diagnostic study
/
Etiology study
/
Experimental Studies
/
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
/
Male
Language:
English
Journal:
J Cardiovasc Electrophysiol
Journal subject:
Vascular Diseases
/
Cardiology
/
Physiology
Year:
2020
Document Type:
Article
Affiliation country:
Jce.14479
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