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Nanomaterials and Nanotechnology-Associated Innovations against Viral Infections with a Focus on Coronaviruses.
Nasrollahzadeh, Mahmoud; Sajjadi, Mohaddeseh; Soufi, Ghazaleh Jamalipour; Iravani, Siavash; Varma, Rajender S.
  • Nasrollahzadeh M; Department of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, Iran.
  • Sajjadi M; Department of Chemistry, Faculty of Science, University of Qom, Qom 37185-359, Iran.
  • Soufi GJ; Radiology Department, School of Medicine, Isfahan University of Medical Sciences, Isfahan 81746 73461, Iran.
  • Iravani S; Faculty of Pharmacy and Pharmaceutical Sciences, Isfahan University of Medical Sciences, Isfahan 81746 73461, Iran.
  • Varma RS; Regional Centre of Advanced Technologies and Materials, Palacký University in Olomouc, Slechtitelu 27, 783 71, CZ-779 00 Olomouc, Czech Republic.
Nanomaterials (Basel) ; 10(6)2020 May 31.
Article in English | MEDLINE | ID: covidwho-436497
Semantic information from SemMedBD (by NLM)
1. Nanotechnology Techniques USES Detection
Subject
Nanotechnology Techniques
Predicate
USES
Object
Detection
2. Prophylactic treatment TREATS Virus Diseases
Subject
Prophylactic treatment
Predicate
TREATS
Object
Virus Diseases
3. Nanotechnology Techniques USES Detection
Subject
Nanotechnology Techniques
Predicate
USES
Object
Detection
4. Prophylactic treatment TREATS Virus Diseases
Subject
Prophylactic treatment
Predicate
TREATS
Object
Virus Diseases
ABSTRACT
Viral infections have recently emerged not only as a health threat to people but rapidly became the cause of universal fatality on a large scale. Nanomaterials comprising functionalized nanoparticles (NPs) and quantum dots and nanotechnology-associated innovative detection methods, vaccine design, and nanodrug production have shown immense promise for interfacing with pathogenic viruses and restricting their entrance into cells. These viruses have been scrutinized using rapid diagnostic detection and therapeutic interventional options against the caused infections including vaccine development for prevention and control. Coronaviruses, namely SARS-CoV, MERS-CoV, and SARS-CoV-2, have endangered human life, and the COVID-19 (caused by SARS-CoV-2) outbreak has become a perilous challenge to public health globally with huge accompanying morbidity rates. Thus, it is imperative to expedite the drug and vaccine development efforts that would help mitigate this pandemic. In this regard, smart and innovative nano-based technologies and approaches encompassing applications of green nanomedicine, bio-inspired methods, multifunctional bioengineered nanomaterials, and biomimetic drug delivery systems/carriers can help resolve the critical issues regarding detection, prevention, and treatment of viral infections. This perspective review expounds recent nanoscience advancements for the detection and treatment of viral infections with focus on coronaviruses and encompasses nano-based formulations and delivery platforms, nanovaccines, and promising methods for clinical diagnosis, especially regarding SARS-CoV-2.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Risk factors Topics: Vaccines Language: English Year: 2020 Document Type: Article Affiliation country: NANO10061072

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Risk factors Topics: Vaccines Language: English Year: 2020 Document Type: Article Affiliation country: NANO10061072