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COVID-19 associated pulmonary aspergillosis.
Koehler, Philipp; Cornely, Oliver A; Böttiger, Bernd W; Dusse, Fabian; Eichenauer, Dennis A; Fuchs, Frieder; Hallek, Michael; Jung, Norma; Klein, Florian; Persigehl, Thorsten; Rybniker, Jan; Kochanek, Matthias; Böll, Boris; Shimabukuro-Vornhagen, Alexander.
  • Koehler P; Department I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Cornely OA; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • Böttiger BW; Department I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Dusse F; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
  • Eichenauer DA; ZKS Köln, Clinical Trials Centre Cologne, Cologne, Germany.
  • Fuchs F; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Hallek M; Department of Anesthesiology and Intensive Care Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Jung N; Department of Anesthesiology and Intensive Care Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Klein F; Department I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Persigehl T; Faculty of Medicine, Institute for Medical Microbiology, Immunology and Hygiene, University of Cologne, Cologne, Germany.
  • Rybniker J; Department I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Kochanek M; Department I of Internal Medicine, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Böll B; Institute of Virology, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
  • Shimabukuro-Vornhagen A; Department of Radiology, Medical Faculty and University Hospital Cologne, University of Cologne, Cologne, Germany.
Mycoses ; 63(6): 528-534, 2020 Jun.
Article in English | MEDLINE | ID: covidwho-547397
ABSTRACT

OBJECTIVES:

Patients with acute respiratory distress syndrome (ARDS) due to viral infection are at risk for secondary complications like invasive aspergillosis. Our study evaluates coronavirus disease 19 (COVID-19) associated invasive aspergillosis at a single centre in Cologne, Germany.

METHODS:

A retrospective chart review of all patients with COVID-19 associated ARDS admitted to the medical or surgical intensive care unit at the University Hospital of Cologne, Cologne, Germany.

RESULTS:

COVID-19 associated invasive pulmonary aspergillosis was found in five of 19 consecutive critically ill patients with moderate to severe ARDS.

CONCLUSION:

Clinicians caring for patients with ARDS due to COVID-19 should consider invasive pulmonary aspergillosis and subject respiratory samples to comprehensive analysis to detect co-infection.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Coronavirus Infections / Pulmonary Aspergillosis Type of study: Case report / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Mycoses Journal subject: Microbiology Year: 2020 Document Type: Article Affiliation country: Myc.13096

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiratory Distress Syndrome / Coronavirus Infections / Pulmonary Aspergillosis Type of study: Case report / Experimental Studies / Observational study / Prognostic study Topics: Long Covid Limits: Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Mycoses Journal subject: Microbiology Year: 2020 Document Type: Article Affiliation country: Myc.13096