COVID-19 and neurological disorders: are neurodegenerative or neuroimmunological diseases more vulnerable?
J Neurol
; 268(2): 409-419, 2021 Feb.
Article
in English
| MEDLINE | ID: covidwho-659027
ABSTRACT
Neurological disorders and coronavirus 2019 (COVID-19) pandemic are two conditions with a recent well-documented association. Intriguing evidences showed that COVID-19 infection can modify clinical spectrum of manifested neurological disorders but also it plays a crucial role in the development of future diseases as long-tem consequences. In this viewpoint review, we aimed to assess the vulnerability to SARS-CoV-2 infection and development of COVID-19 among neurological disorders. With this in mind, we tested the hypothesis that age rather than neuropathology itself could be decisive in neurodegenerative diseases such as Parkinson's disease, whereas neuropathology rather than age may be critical in neuroimmunological diseases such as Multiple Sclerosis. Highlighting the role of potential susceptibility or protection factors from this disastrous infection, we also stratify the risk for future neurodegeneration.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Neurodegenerative Diseases
/
COVID-19
/
Immune System Diseases
/
Nervous System Diseases
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
J Neurol
Year:
2021
Document Type:
Article
Affiliation country:
S00415-020-10070-8
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