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Covid-19.bioreproducibility.org: A web resource for SARS-CoV-2-related structural models.
Brzezinski, Dariusz; Kowiel, Marcin; Cooper, David R; Cymborowski, Marcin; Grabowski, Marek; Wlodawer, Alexander; Dauter, Zbigniew; Shabalin, Ivan G; Gilski, Miroslaw; Rupp, Bernhard; Jaskolski, Mariusz; Minor, Wladek.
  • Brzezinski D; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
  • Kowiel M; Center for Biocrystallographic Research, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
  • Cooper DR; Institute of Computing Science, Poznan University of Technology, Poznan, Poland.
  • Cymborowski M; Center for Biocrystallographic Research, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
  • Grabowski M; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
  • Wlodawer A; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
  • Dauter Z; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
  • Shabalin IG; Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, Maryland, USA.
  • Gilski M; Macromolecular Crystallography Laboratory, National Cancer Institute, Frederick, Maryland, USA.
  • Rupp B; Department of Molecular Physiology and Biological Physics, University of Virginia, Charlottesville, Virginia, USA.
  • Jaskolski M; Center for Biocrystallographic Research, Institute of Bioorganic Chemistry, Polish Academy of Sciences, Poznan, Poland.
  • Minor W; Department of Crystallography, Faculty of Chemistry, Adam Mickiewicz University, Poznan, Poland.
Protein Sci ; 30(1): 115-124, 2021 01.
Article in English | MEDLINE | ID: covidwho-796087
ABSTRACT
The COVID-19 pandemic has triggered numerous scientific activities aimed at understanding the SARS-CoV-2 virus and ultimately developing treatments. Structural biologists have already determined hundreds of experimental X-ray, cryo-EM, and NMR structures of proteins and nucleic acids related to this coronavirus, and this number is still growing. To help biomedical researchers, who may not necessarily be experts in structural biology, navigate through the flood of structural models, we have created an online resource, covid19.bioreproducibility.org, that aggregates expert-verified information about SARS-CoV-2-related macromolecular models. In this article, we describe this web resource along with the suite of tools and methodologies used for assessing the structures presented therein.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viral Proteins / Internet / SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Protein Sci Journal subject: Biochemistry Year: 2021 Document Type: Article Affiliation country: Pro.3959

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Viral Proteins / Internet / SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Protein Sci Journal subject: Biochemistry Year: 2021 Document Type: Article Affiliation country: Pro.3959