At the peak of COVID-19 age and disease severity but not comorbidities are predictors of mortality: COVID-19 burden in Bergamo, Italy.
Panminerva Med
; 63(1): 51-61, 2021 Mar.
Artigo
em Inglês
| MEDLINE | ID: covidwho-1068211
ABSTRACT
BACKGROUND:
Findings from February 2020, indicate that the clinical spectrum of COVID-19 can be heterogeneous, probably due to the infectious dose and viral load of SARS-CoV-2 within the first weeks of the outbreak. The aim of this study was to investigate predictors of overall 28-day mortality at the peak of the Italian outbreak.METHODS:
Retrospective observational study of all COVID-19 patients admitted to the main hospital of Bergamo, from February 23 to March 14, 2020.RESULTS:
Five hundred and eight patients were hospitalized, predominantly male (72.4%), mean age of 66±15 years; 49.2% were older than 70 years. Most of patients presented with severe respiratory failure (median value [IQR] of PaOCONCLUSIONS:
At the peak of the outbreak, with a probable high infectious dose and viral load, older age, the severity of respiratory failure and renal impairment at presentation, but not comorbidities, are predictors of 28-day mortality in COVID-19.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Assunto principal:
Fatores Etários
/
COVID-19
Tipo de estudo:
Estudo observacional
/
Estudo prognóstico
Tópicos:
Covid persistente
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
/
Meia-Idade
País/Região como assunto:
Europa
Idioma:
Inglês
Revista:
Panminerva Med
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
S0031-0808.20.04063-X
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