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Persistent anosmia after COVID-19 Infection: Treatment options according to BDORT
Acupuncture and Electro-Therapeutics Research ; 46(1):33-34, 2021.
Artigo em Inglês | EMBASE | ID: covidwho-1264550
ABSTRACT
The current outbreak of the novel coronavirus SARS-CoV-2 (coronavirus disease 2019), epi-centered in Hubei Province of the People's Republic of China, has spread to many other countries. On January 30th, 2020, the WHO Emergency Committee declared a global health emergency based on growing case notification rates at Chinese and international locations. Coronaviruses are enveloped, positive single-stranded large RNA viruses that infect humans, but also a wide range of animals. Coronaviruses were first described in 1966 by Tyrell and Bynoe, who cultivated the viruses from patients with common colds. Four subfamilies, namely alpha-, beta-, gamma- and delta-coronaviruses, exist. While alpha- and beta-coronaviruses apparently originate from mammals, particularly from bats, gamma- and delta-viruses originate from pigs and birds. Among seven subtypes of coronaviruses that can infect humans, beta-coronaviruses may cause severe disease and fatalities, whereas alphacoronaviruses cause asymptomatic or mildly symptomatic infections. SARS-CoV-2 belongs to the B lineage of the beta-coronaviruses and is closely related to the SARS-CoV virus. The coronavirus related disease caused by SARS-CoV-2 has been named COVID- 19. Symptoms at the onset of COVID-19 infection may include fever, cough, fatigue, myalgia, sputum production, dyspnea, oppression in the chest, diarrhea, headache, anorexia, chest pain, sore throat, dizziness, palpitations, and vomiting. The infection can progress to severe disease with pneumonia and death. Although coronaviruses are known to cause a common cold, and olfactory loss is known to be associated with common cold, many reports related anosmia (loss of sense of smell) and also dysgeusia (alteration of sense of taste) as primary and pathognomonic symptom of COVID-19. This feature may indicate a propensity for neuroinvasion;olfactory neurons are currently being discussed as a portal of entry for neuroinvasion and the spread of COVID-19 after infection of neural cells from the CNS to the periphery via a transneuronal route. The majority of patients who developed anosmia and/or dysgeusia with a confirmed diagnosis of COVID-19 by PCR-RT test or serum antibodies test have recovered after 15 days;a few cases recovered after 30 days. We present three cases of patients who did not recover after up to three months from the onset of the infection by COVID-19. One case was a 65-year-old male with positive PCR-RT for COVID-19 before the consultation. He was complaining of loss of smell since the onset of infection three months before, with no improvement. According to BDORT, there was a positive resonance to COVID-19 infection (using a virus picture), and research for a drug aid found Açaí berry positive. The patient took the medication for a week, with good improvement. Another case was a 35-year-old female complaining of anosmia for 45 days;no diagnosis of COVID-19 was performed. Brain MRI was normal. BDORT was positive for COVID-19, and for Omega-3 fish oil, that was prescribed, with an improvement of olfaction in two weeks. Last case was a 45-year-old woman with a previous diagnosis of COVID-19 by PCR-RT and loss of smell for two months before the consultation. She was submitted to Ozone therapy by ear insufflation;later, she informed the sense of smell improved that same day. We conclude that there are therapeutic options out of sight of medical literature that can be useful for controlling the COVID-19 pandemic, and the BDORT is important to find those solutions with the advantage of time-saving. Until now, no specific antiviral drug has been proven effective for the treatment of patients with severe COVID-19. Ozone therapy by ear insufflation can also be an important aid in COVID-19 infection because nose and paranasal sinuses are areas of great concentration of the virus due to the mechanism of infection involving the respiratory epithelium.

Texto completo: Disponível Coleções: Bases de dados de organismos internacionais Base de dados: EMBASE Tópicos: Covid persistente Idioma: Inglês Revista: Acupuncture and Electro-Therapeutics Research Ano de publicação: 2021 Tipo de documento: Artigo

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Texto completo: Disponível Coleções: Bases de dados de organismos internacionais Base de dados: EMBASE Tópicos: Covid persistente Idioma: Inglês Revista: Acupuncture and Electro-Therapeutics Research Ano de publicação: 2021 Tipo de documento: Artigo