Aging and Options to Halt Declining Immunity to Virus Infections.
Front Immunol
; 12: 681449, 2021.
Artigo
em Inglês
| MEDLINE | ID: covidwho-1314554
ABSTRACT
Immunosenescence is a process associated with aging that leads to dysregulation of cells of innate and adaptive immunity, which may become dysfunctional. Consequently, older adults show increased severity of viral and bacterial infections and impaired responses to vaccinations. A better understanding of the process of immunosenescence will aid the development of novel strategies to boost the immune system in older adults. In this review, we focus on major alterations of the immune system triggered by aging, and address the effect of chronic viral infections, effectiveness of vaccination of older adults and strategies to improve immune function in this vulnerable age group.
Palavras-chave
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Assunto principal:
Viroses
/
Envelhecimento
/
Interações Hospedeiro-Patógeno
/
Imunidade
Tipo de estudo:
Estudo prognóstico
Tópicos:
Vacinas
Limite:
Animais
/
Humanos
Idioma:
Inglês
Revista:
Front Immunol
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
Fimmu.2021.681449
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