Role of high dose oral liposomal vitamin -C in reducing mortality in patients with COVID-19

ABSTRACT

Introduction: Severe cases of COVID-19 are associated with hypoxemic respiratory failure, acute respiratory distress syndrome (ARDS), septic shock, cardiac dysfunction, elevation in multiple inflammatory cytokines, thrombo embolic disease, and/or exacerbation of underlying co morbidities. In addition to pulmonary disease, patients with COVID-19 may also experience cardiac, hepatic, renal, and central nervous system disease. AIM OF THE STUDY;To describe the role and outcome, of high-dose of oral liposomal vitamin C treatment in reducing mortality in Covid-19 patients admitted in Government Medical College & ESI Hospital, Coimbatore, India. Materials and methods: Patients who admitted with the diagnosis of COVID-19 by RTPCR in government medical college and ESI hospital Coimbatore during 1 th march 2021 to may 31,2021 are taken for this retrospective study. Of the 8634 patients admitted 5422(62%) required non oxygen beds. -2989(34%) required oxygen beds on admission -223 patients(2.5%) required beds (with,98 on c pap, 34 ventilators,64 high flow nasal oxygen, 43 non re-breathing mask and 58 non invasive ventilators), all outcomes are compared with same type of patients admitted in similar hospital and similar set of patients, without high dose vitamin c.