Your browser doesn't support javascript.
Age-related risk factors and severity of SARS-CoV-2 infection: A systematic review and meta-analysis
Journal of Preventive Medicine and Hygiene ; 62(2):E329-E371, 2021.
Artigo em Inglês | EMBASE | ID: covidwho-1355287
ABSTRACT
Objectives. We aimed to estimate the prevalence of reported symptoms and comorbidities, and investigate the factors associated with age of the SARS-CoV-2 infected patients. Methods. We performed a systematic review with meta-analysis (PROSPERO registration CRD42020182677) where the databases (PubMed, SCOPUS, EMBASE, WHO, Semantic Scholar, and COVID-19 Primer) were searched for clinical studies published from January to April, 2020. Initially, the pooled prevalence of symptoms and comorbidity of COVID-19 patients were estimated using random effect model and the age –related factors were identified performing multivariate analysis [factor analysis]. Results. Twenty-nine articles with 4,884 COVID-19 patients were included in this study. Altogether, we found 33 symptoms and 44 comorbidities where the most frequent 19 symptoms and 11 comorbidities were included in the meta-analysis. The fever (84%), cough/dry cough (61%), and fatigue/weakness (42%) were found more prevalent while acute respiratory distress syndrome, hypertension and diabetes were the most prevalent comorbid condition. The factor analysis showed positive association between a cluster of symptoms and comorbidities with patients’ age. The symptoms comprising fever, dyspnea/shortness of breath, nausea, vomiting, abdominal pain, dizziness, anorexia and pharyngalgia;and the comorbidities including diabetes, hypertension, coronary heart disease, COPD/lung disease and ARDS were the factors positively associated with COVID-19 patient’s age. Conclusion. As an unique effort, this study found a group of symptoms (fever, dyspnea/shortness of breath, nausea, vomiting, abdominal pain, dizziness, anorexia and pharyngalgia) and comorbidities (diabetes, hypertension, coronary heart disease, COPD/lung disease and ARDS), associated with the age of COVID-19 infected patients.

Texto completo: Disponível Coleções: Bases de dados de organismos internacionais Base de dados: EMBASE Tipo de documento: Artigo Tipo de estudo: Estudo de etiologia / Estudo prognóstico / Fatores de risco / Revisão sistemática Idioma: Inglês Revista: Journal of Preventive Medicine and Hygiene Ano de publicação: 2021

Similares

MEDLINE

...
LILACS

LIS


Texto completo: Disponível Coleções: Bases de dados de organismos internacionais Base de dados: EMBASE Tipo de documento: Artigo Tipo de estudo: Estudo de etiologia / Estudo prognóstico / Fatores de risco / Revisão sistemática Idioma: Inglês Revista: Journal of Preventive Medicine and Hygiene Ano de publicação: 2021
...