Dynamics of Antibodies to Various Antigens of the SARS-CoV-2 Coronavirus in Patients with Confirmed COVID-19 Infection.
Bull Exp Biol Med
; 171(2): 230-233, 2021 May.
Artigo
em Inglês
| MEDLINE | ID: covidwho-1525548
ABSTRACT
The presence of IgG and IgM antibodies in the venous blood of 76 patients with confirmed COVID-19 infection was determined by ELISA using Russian test systems. Different levels of IgM antibodies to N-protein and receptor binding domain of the Spike protein (RBD) were revealed. The dynamics of IgG antibodies to the whole virion antigen and recombinant antigens showed high values on weeks 4-5 of the disease. The level of IgG antibodies to Nprotein remained low throughout the observation period. The characteristic dynamics of IgG measured using test systems with sorbed whole virion or recombinant spike proteins reflects the duration of the disease.
Palavras-chave
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Assunto principal:
Imunoglobulina G
/
Imunoglobulina M
/
Glicoproteína da Espícula de Coronavírus
/
Proteínas do Nucleocapsídeo de Coronavírus
/
COVID-19
/
Anticorpos Antivirais
/
Antígenos Virais
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Inglês
Revista:
Bull Exp Biol Med
Ano de publicação:
2021
Tipo de documento:
Artigo
País de afiliação:
S10517-021-05200-9
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