EFFECTIVENESS OF LILLY CONNECTED CARE PROGRAM IN IMPROVING GLYCEMIC MANAGEMENT AMONG CHINESE TYPE 2 DIABETES PATIENTS: A RETROSPECTIVE REAL-WORLD STUDY

ABSTRACT

Background and Aims: Mobile health management platform is a potential way to achieving effective glycemic control in type 2 diabetesmellitus (T2DM) patients, especially during the Covid-19 pandemic. Lilly Connected Care Program (LCCP) is a smartphone-based app providing blood glucose monitoring and diabetes education services to improve diabetes management. This study aimed to evaluate the real-world effectiveness of LCCP platform in glycemic control among Chinese T2DM patients. Methods: This retrospective study included Chinese T2DM patients (age ≥18 years) from January 1, 2015, to January 31, 2020. Data was drawn from mobile app and electronic medical records. Propensity score matching (PSM) was used to match LCCP group and non-LCCP group to reduce confounding, with covariates including age, sex, duration of diabetes, baseline HbA1c, and number of oral diabetes medication classes. We analyzed HbA1c reduction within an average of 4 months and compared the proportions of patients achieving HbA1c reduction ≥0.5% or ≥1% between LCCP and non-LCCP groups. Comparisons were made using independent t-test and Chi-square test. Results: A total of 923 patients were included, among whom 303 pairs of patients were well-matched after PSM (Standardized Mean Difference of covariates <15%). The HbA1c reduction during 4-month follow-up was significantly larger in LCCP group than non-LCCP group (Mean±SD 2.21 ± 2.37% vs. 1.65 ± 2.29%, P = 0.003). LCCP group had higher proportions of patients with HbA1c reduction ≥1% (69.0% vs. 57.4%, P = 0.003) and ≥0.5% (75.6% vs. 68.0%, P = 0.038). Conclusions: LCCP mobile platform was effective in glycemic control among Chinese T2DM patients in the real world.