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COLLAPSING FOCAL-SEGMENTAL GLOMERULOSCLEROSIS POST COVID-19
General Medicine ; 24(3):32-35, 2022.
Artigo em Búlgaro | EMBASE | ID: covidwho-1976323
ABSTRACT
The glomerular lesions with COVID-19 are uncommon, but include cases of a collapse type of a focal-segmental glomerulosclerosis, occurring during the active infection. Of interest is the establishment of this glomerular disease as a manifestation of a post-COVID-19 damage, occurring at some point after the illness. The case of an 84-year-old woman with a nephrotic syndrome and elevated serum creatinine is presented. Two months earlier the patient had COVID-19 with a bilateral pneumonia as a complication. During the hospital admission she was in a poor general condition. Blood pressure was 220/100 mm Hg. Expressed swelling around the ankles and feet was seen. From the tests ‒ ESR ‒ 147, CRP ‒ 19, total protein ‒ 48 g/l, albumin ‒ 16 g/l, cholesterol ‒ 11.3 mmol/l, triglycerides ‒ 5.3 mmol/l, creatinine ‒ 362 μmol/l, urea ‒ 19.4 mmol/l. Proteinuria ‒ 19.2 g/24 hours. Urine sediment ‒ 3 leukocytes, 20 erythrocytes. Renal biopsy revealed focal-segmental glomerulosclerosis, collapse type. Treatment with corticosteroids and anticoagulants was performed. The patient’s condition improved ‒ the nephrotic syndrome disappeared, serum creatinine was reduced to upper limit values, arterial hypertension was controlled with small amounts of medication. The occurrence of a renal impairment as a late complication of COVID-19 is a possible result of an infection-related immune dysregulation.
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Coleções: Bases de dados de organismos internacionais Base de dados: EMBASE Tópicos: Covid persistente Idioma: Búlgaro Revista: General Medicine Ano de publicação: 2022 Tipo de documento: Artigo

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Coleções: Bases de dados de organismos internacionais Base de dados: EMBASE Tópicos: Covid persistente Idioma: Búlgaro Revista: General Medicine Ano de publicação: 2022 Tipo de documento: Artigo