COLLAPSING FOCAL-SEGMENTAL GLOMERULOSCLEROSIS POST COVID-19
General Medicine
; 24(3):32-35, 2022.
Artigo
em Búlgaro
| EMBASE | ID: covidwho-1976323
ABSTRACT
The glomerular lesions with COVID-19 are uncommon, but include cases of a collapse type of a focal-segmental glomerulosclerosis, occurring during the active infection. Of interest is the establishment of this glomerular disease as a manifestation of a post-COVID-19 damage, occurring at some point after the illness. The case of an 84-year-old woman with a nephrotic syndrome and elevated serum creatinine is presented. Two months earlier the patient had COVID-19 with a bilateral pneumonia as a complication. During the hospital admission she was in a poor general condition. Blood pressure was 220/100 mm Hg. Expressed swelling around the ankles and feet was seen. From the tests ‒ ESR ‒ 147, CRP ‒ 19, total protein ‒ 48 g/l, albumin ‒ 16 g/l, cholesterol ‒ 11.3 mmol/l, triglycerides ‒ 5.3 mmol/l, creatinine ‒ 362 μmol/l, urea ‒ 19.4 mmol/l. Proteinuria ‒ 19.2 g/24 hours. Urine sediment ‒ 3 leukocytes, 20 erythrocytes. Renal biopsy revealed focal-segmental glomerulosclerosis, collapse type. Treatment with corticosteroids and anticoagulants was performed. The patient’s condition improved ‒ the nephrotic syndrome disappeared, serum creatinine was reduced to upper limit values, arterial hypertension was controlled with small amounts of medication. The occurrence of a renal impairment as a late complication of COVID-19 is a possible result of an infection-related immune dysregulation.
aged; ankle; article; bilateral pneumonia; blood pressure; case report; clinical article; collapse; complication; coronavirus disease 2019; creatinine blood level; drug combination; erythrocyte; female; focal glomerulosclerosis; foot; hospital admission; human; human cell; human tissue; hypertension; immune dysregulation; kidney biopsy; kidney disease; leukocyte; low drug dose; nephrotic syndrome; poor general condition; proteinuria; swelling; urine sediment; very elderly; albumin; anticoagulant agent; cholesterol; corticosteroid; endogenous compound; protein; triacylglycerol; urea
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Coleções:
Bases de dados de organismos internacionais
Base de dados:
EMBASE
Tópicos:
Covid persistente
Idioma:
Búlgaro
Revista:
General Medicine
Ano de publicação:
2022
Tipo de documento:
Artigo
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