Single organ hepatic artery vasculitis as an unusual cause of epigastric pain: A case report.
World J Clin Cases
; 10(26): 9384-9389, 2022 Sep 16.
Artigo
em Inglês
| MEDLINE | ID: covidwho-2033421
ABSTRACT
BACKGROUND:
Single-organ vasculitis (SOV) is characterized by inflammation of a blood vessel, affecting one organ, such as the skin, genitourinary system, or the aorta without systemic features. Gastrointestinal SOV is rare, with hepatic artery involvement reported only in two prior published cases. Herein, we presented a case of isolated hepatic artery vasculitis presenting after Pfizer-BioNTech mRNA corona virus disease 2019 (COVID-19) vaccination. CASESUMMARY:
A 50-year-old woman with hypertension presented to our Emergency Department with recurrent diffuse abdominal pain that localized to the epigastrium and emesis without diarrhea that began eight days after the second dose of the Pfizer-BioNTech COVID-19 vaccine. Blood work revealed an elevated C-reactive protein (CRP) of 19 mg/L (normal < 4.8 mg/L), alkaline phosphatase 150 U/L (normal 25-105 U/L), gamma-glutamyl transferase (GGT) 45 U/L (normal < 43 U/L) and elevated immunoglobulins (Ig) G 18.4 g/L (normal 7-16 g/L) and IgA 4.4 g/L (normal 0.7-4 g/L). An abdominal computed tomography revealed findings in keeping with hepatic artery vasculitis. A detailed review of her history and examination did not reveal infectious or systemic autoimmune causes of her presentation. An extensive autoimmune panel was unremarkable. COVID-19 polymerase chain reaction nasopharyngeal swab, human immunodeficiency virus, viral hepatitis and Heliobacter pylori serology were negative. At six months, the patient's symptoms, and blood work spontaneously normalized.CONCLUSION:
High clinical suspicion of SOV is required for diagnosis in patients with acute abdominal pain and dyspepsia.
Texto completo:
Disponível
Coleções:
Bases de dados internacionais
Base de dados:
MEDLINE
Tipo de estudo:
Relato de caso
/
Estudo prognóstico
Tópicos:
Vacinas
Idioma:
Inglês
Revista:
World J Clin Cases
Ano de publicação:
2022
Tipo de documento:
Artigo
País de afiliação:
Wjcc.v10.i26.9384
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