On the Problem of Optimal Microbiological Decontamination of Air Environment and Surfaces

ABSTRACT

Modern civilization, providing economic and social progress, at the same time objectively creates—sometimes close to ideal—conditions for the spread of various infections. The catastrophic consequences of the SARS-CoV-2 pandemic clearly indicate that homo sapiens appeared to be unable to effectively resist the onslaught of the coronavirus. The purpose of this publication is an attempt to fill the gap in the development of effective methods and means for microbiological decontamination that are optimal in terms of critical parameters. The observational data indicate that a significant number of SARS-CoV-2 coronavirus infections occur by air without a direct contact with the source, including over a long time interval. Precipitation helps to cleanse the air from pollutants and viruses, reducing noncontact contamination, which additionally brings up to date the problem of optimal microbiological decontamination of the air environment and surfaces. A thermodynamic approach has been used to optimize microbiological sterilization. It is shown that irreversible chemical oxidation reactions are the shortest way to achieve sterility, and they are capable of providing high reliability of decontamination. It has been established that oxygen is an optimal oxidant, including from the point of view of ecology, since its reactive forms harmoniously fit into natural exchange cycles. The optimal method for obtaining reactive oxygen species for disinfection is the use of low-temperature (“cold”) plasma, which provides the energy-efficient generation of oxidative reactive forms atomic oxygen (O), ozone (O3), hydroxyl radical (•OH), hydrogen peroxide (H2O2), superoxide (