Serum Albumin And C-Reactive Protein/ Albumin Ratio On Admission As Prognostic Predictors In Sars-Cov-2 Infection: A Retrospective Study

ABSTRACT

The salient objective of this research was to assess the serum albumin levels and C-reactive protein /albumin ratio in the admitted cases of SARS-CoV-2 in a tertiary care hospital, we tried to predict the severity of the disease like increased oxygen requirement during the hospital stay and on discharge, intensive care unit (ICU) requirement, longer hospital stay and secondary infections during the hospital stay by assessing by the C-reactive protein /albumin ratio biomarker. The study was conducted as a retrospective observational one, a total of 200 SARS-CoV-2 infected subjects were considered for the study, and each subject was carefully examined and data collected. Based on the objective of interest we correlated Serum Albumin levels and C-reactive protein /Albumin Ratio at the time of admission and subsequent clinical course of patient was noted. As per the findings, the mean CRP was 2.68 g/L in mild cases;moderate was 6.38 g/L, and severe was 7.44 g/L. The higher CRP is significantly associated with a tendency for respiratory distress, increased requirement of high flow oxygen treatment and patients requiring mechanical ventilation. CRP/Alb ratio on the mean differences was 0.386, the serum albumin level significantly differed at 1% level. In conclusion, CRP/alb ratio is a valid Biomarker for treating SARS-CoV-2 patients and provides substantial information to the clinicians for making a valid decision at the right time. Copyright © 2022, Anka Publishers. All rights reserved.