Combined Immunization of COVID-19 Inactivated Vaccine With QIV and PPV23

ABSTRACT

ConditionSafety;Immunogenicity, Vaccine;COVID-19 Vaccines;Influenza Vaccines;Pneumococcal Vaccines

InterventionBiological Vaccine

Primary outcome:Seroconversion rate of neutralizing antibody

Criteria
Inclusion Criteria

- Healthy adults 18 years old and older

- Over 6 months after primary immunization with COVID-19 vaccines

- Can understand and sign the consent

- Can provide effective personal identification

Exclusion Criteria

- Has a history of COVID-19 infection

- Less than 6 months after primary immunization with COVID-19 vaccines

- Already vaccinated with influenza vaccines of that year

- Vaccinated with pneumococcal vaccines within 5 years

- Has a history of severe hypersensitivity reaction to vaccines

- Has uncontrolled seizure or other severe neural system illnesses

- Has a fever, chronic disease, or acute disease during immunization

- Gestation period, lactation period, or planning to get pregnant within 3 months

- Administrated with other drugs under research within 30 days before vaccination

- Received attenuated vaccines within 14 days before vaccination

- Received subunit vaccines or inactivated vaccines within 7 days before vaccination

- Other conditions based on researcher's judgement