Evaluation of Bleeding Rate and Time in Therapeutic Range in Patients Using Warfarin Before and During the COVID-19 Pandemic-Warfarin Treatment in COVID-19.
Clin Appl Thromb Hemost
; 27: 10760296211021495, 2021.
Статья
в английский
| MEDLINE | ID: covidwho-1277870
ABSTRACT
The treatment process of patients using warfarin is expected to be hindered during the COVID-19 pandemic. Therefore we investigated whether the time in therapeutic range (TTR) and bleeding complications were affected during the COVID-19 pandemic. 355 patients using warfarin were included between March 2019 to March 2021. Demographic parameters, INR (international normalized ratio), and bleeding rates were recorded retrospectively. The TTR value was calculated using Rosendaal's method. The mean age of the patients was 61 ± 12 years and 55% of them were female. The mean TTR value during the COVID-19 pandemic was lower than the pre-COVID-19 period (56 ± 21 vs 68 ± 21, P < 0.001). Among the patients, 41% had a lack of outpatient INR control. During the COVID-19 pandemic, 71 (20%) patients using VKA suffered bleeding. Among patients with bleeding, approximately 60% did not seek medical help and 6% of patients performed self-reduction of the VKA dose. During the COVID-19 pandemic, TTR values have decreased with the lack of monitoring. Furthermore, the majority of patients did not seek medical help even in case of bleeding.
ключевые слова
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
Warfarin
/
Bleeding Time
/
Blood Coagulation
/
Thrombophilia
/
International Normalized Ratio
/
Pandemics
/
SARS-CoV-2
/
COVID-19
/
Hemorrhage
/
Anticoagulants
Тип исследования:
Экспериментальные исследования
/
Наблюдательное исследование
/
Прогностическое исследование
/
Качественное исследование
Темы:
Длинный Ковид
Пределы темы:
Пожилые
/
Женщины
/
Люди
/
Мужчины
/
Middle aged
Язык:
английский
Журнал:
Clin Appl Thromb Hemost
Тематика журнала:
Болезни системы кровообращения
Год:
2021
Тип:
Статья
Аффилированная страна:
10760296211021495
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