Comparison of epidemiological and clinical characteristics of COVID-19 patients with and without Wuhan exposure / 浙江省有无武汉暴露史新型冠状肺炎患者的流行 病学和临床特征的比较研究
J. Zhejiang Uni. Sci. B
; 5(21): 369-377, 20200501.
Статья
в английский
| WHO COVID, ELSEVIER | ID: covidwho-1352747
ABSTRACT
Background:
A novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first identified in Wuhan, China, has been rapidly spreading around the world. This study investigates the epidemiological and clinical characteristics of coronavirus disease 2019 (COVID-19) patients in Zhejiang Province who did or did not have a history of Wuhan exposure.Methods:
We collected data from medical records of confirmed COVID-19 patients in Zhejiang Province from Jan. 17 to Feb. 7, 2020 and analyzed epidemiological, clinical, and treatment data of those with and without recorded recent exposure in Wuhan.Results:
Patients in the control group were older than those in the exposure group ((48.19±16.13) years vs. (43.47±13.12) years, P<0.001), and more were over 65 years old (15.95% control vs. 5.60% exposure, P<0.001). The rate of clustered onset was also significantly higher in the control group than in the exposure group (31.39% vs. 18.66%, P<0.001). The symptom of a sore throat in patients in the exposure group was significantly higher than that in the control group (17.30% vs. 10.89%, P=0.01); however, headache in the exposure group was significantly lower than that in the control group (6.87% vs. 12.15%, P=0.015). More patients in the exposure group had a significantly lower level of lactate dehydrogenase (LDH) and aspartate aminotransferase (AST) than those in the control group. There was no significant difference in any degree of COVID-19 including mild, severe, and critical between the two groups.Conclusions:
From the perspective of epidemiological and clinical characteristics, there was no significant difference between COVID-19 patients with and without Wuhan exposure history.
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
WHO COVID
/
ELSEVIER
Тип исследования:
Наблюдательное исследование
/
Прогностическое исследование
Язык:
английский
Журнал:
J. Zhejiang Uni. Sci. B
Год:
2020
Тип:
Статья
Учреждение/Аффилированная страна:
Department of Gastroenterology/China
/
State Key Laboratory for Diagnosis and Treatment of Infectious Diseases/China
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