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Persistence of post-COVID lung parenchymal abnormalities during the three-month follow-up.
Zubairi, Ali Bin Sarwar; Shaikh, Anjiya; Zubair, Syed Muhammad; Ali, Akbar Shoukat; Awan, Safia; Irfan, Muhammad.
  • Zubairi ABS; Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan. ali.zubairi@aku.edu.
  • Shaikh A; Medical College, Aga Khan University, Karachi, Pakistan.
  • Zubair SM; Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
  • Ali AS; Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
  • Awan S; Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
  • Irfan M; Department of Medicine, Aga Khan University Hospital, Karachi, Pakistan.
Adv Respir Med ; 89(5): 477-483, 2021.
Статья в английский | MEDLINE | ID: covidwho-1456468
ABSTRACT

INTRODUCTION:

COVID-19-associated pulmonary sequalae have been increasingly reported after recovery from acute infection. Therefore, we aim to explore the charactersitics of persistent lung parenchymal abnormalities in patients with COVID-19. MATERIAL AND

METHODS:

An observational study was conducted in patients with post-COVID lung parenchymal abnormalities from April till September 2020. Patients ≥18 years of age with COVID-19 who were diagnosed as post-COVID lung parenchymal abnormality based on respiratory symptoms and HRCT chest imaging after the recovery of acute infection. Data was recorded on a structured pro forma, and descriptive analysis was performed using Stata version 12.1.

RESULTS:

A total of 30 patients with post-COVID lung parenchymal abnormalities were identified. The mean age of patients was 59.1 (SD 12.6), and 27 (90.0%) were males. Four HRCT patterns of lung parenchymal abnormalities were seen; organizing pneumonia in 10 (33.3%), nonspecific interstitial pneumonitis in 17 (56.7%), usual interstitial pneumonitis in 12 (40.0%) and probable usual interstitial pneumonitis in 14 (46.7%). Diffuse involvement was found in 15 (50.0%) patients, while peripheral predominance in 15 (50.0%), and other significant findings were seen in 8 (26.7%) patients. All individuals were treated with corticosteroids. The case fatality rate was 16.7%. Amongst the survivors, 32.0% recovered completely, 36.0% improved, while 32.0% of the patients had static or progressive disease.

CONCLUSION:

This is the first study from Southeast Asia that identified post-COVID lung parenchymal abnormalities in patients who had no pre-existing lung disease highlighting the importance of timely recognition and treatment of this entity that might lead to fatal outcome.
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Полный текст: Имеется в наличии Коллекция: Международные базы данных база данных: MEDLINE Основная тема: Pulmonary Fibrosis / COVID-19 Тип исследования: Когортное исследование / Наблюдательное исследование / Прогностическое исследование Темы: Длинный Ковид Пределы темы: Взрослые / Женщины / Люди / Мужчины / Middle aged Язык: английский Журнал: Adv Respir Med Год: 2021 Тип: Статья Аффилированная страна: ARM.a2021.0090

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Полный текст: Имеется в наличии Коллекция: Международные базы данных база данных: MEDLINE Основная тема: Pulmonary Fibrosis / COVID-19 Тип исследования: Когортное исследование / Наблюдательное исследование / Прогностическое исследование Темы: Длинный Ковид Пределы темы: Взрослые / Женщины / Люди / Мужчины / Middle aged Язык: английский Журнал: Adv Respir Med Год: 2021 Тип: Статья Аффилированная страна: ARM.a2021.0090