Symptom-Based Predictive Model of COVID-19 Disease in Children.
Viruses
; 14(1)2021 12 30.
Статья
в английский
| MEDLINE | ID: covidwho-1580399
ABSTRACT
BACKGROUND:
Testing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is neither always accessible nor easy to perform in children. We aimed to propose a machine learning model to assess the need for a SARS-CoV-2 test in children (<16 years old), depending on their clinical symptoms.METHODS:
Epidemiological and clinical data were obtained from the REDCap® registry. Overall, 4434 SARS-CoV-2 tests were performed in symptomatic children between 1 November 2020 and 31 March 2021, 784 were positive (17.68%). We pre-processed the data to be suitable for a machine learning (ML) algorithm, balancing the positive-negative rate and preparing subsets of data by age. We trained several models and chose those with the best performance for each subset.RESULTS:
The use of ML demonstrated an AUROC of 0.65 to predict a COVID-19 diagnosis in children. The absence of high-grade fever was the major predictor of COVID-19 in younger children, whereas loss of taste or smell was the most determinant symptom in older children.CONCLUSIONS:
Although the accuracy of the models was lower than expected, they can be used to provide a diagnosis when epidemiological data on the risk of exposure to COVID-19 is unknown.ключевые слова
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
COVID-19 Testing
/
SARS-CoV-2
/
COVID-19
Тип исследования:
Диагностическое исследование
/
Наблюдательное исследование
/
Прогностическое исследование
Пределы темы:
Подростки
/
Дети
/
Детский дошкольный
/
Женщины
/
Люди
/
Грудные дети
/
Мужчины
/
Новорожденные
Язык:
английский
Год:
2021
Тип:
Статья
Аффилированная страна:
V14010063
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