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Investigation of the ongoing pulmonary defects with perfusion-single photon emission computed tomography/computed tomography in patients under anticoagulant therapy for coronavirus disease 2019-induced pulmonary embolism.
Caliskaner Ozturk, Buket; Atahan, Ersan; Kibar, Ali; Sager, Sait; Borekci, Sermin; Gemicioglu, Bilun.
  • Caliskaner Ozturk B; Departments of Pulmonary Diseases.
  • Atahan E; Departments of Pulmonary Diseases.
  • Kibar A; Nuclear Medicine, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Sager S; Nuclear Medicine, Cerrahpasa Faculty of Medicine, Istanbul University-Cerrahpasa, Istanbul, Turkey.
  • Borekci S; Departments of Pulmonary Diseases.
  • Gemicioglu B; Departments of Pulmonary Diseases.
Nucl Med Commun ; 43(9): 978-986, 2022 09 01.
Статья в английский | MEDLINE | ID: covidwho-1985179
ABSTRACT

OBJECTIVE:

It was aimed to reveal the continuing perfusion defect rates in patients with a diagnosis of pulmonary embolism (PE) due to COVID-19 who have completed the third month of anticoagulant therapy but whose symptoms or laboratory elevations continue.

METHODS:

Patients with COVID-19 who were diagnosed with PE by Q-SPECT-CT between 1 September 2020 and 1 November 2021, who underwent control Q-SPECT/CT were included in the study. Demographic characteristics, laboratory findings, and first and second Q-SPECT/CT evaluation results of the patients were recorded.

RESULTS:

It was observed that the pulmonary defect continued in Q-SPECT/CT in the third month of anticoagulant treatment in 58.3% of the patients diagnosed with PE due to COVID-19, and new defects developed in 6.3%. The persistence rate of segment defects was higher than that of subsegment defects. It was observed that the defects persisted more frequently in patients with a history of hospitalization due to COVID-19.

CONCLUSION:

Perfusion defects may still be present in patients diagnosed with PE due to COVID-19 in the presence of persistent dyspnea/chest pain/D-dimer elevation after 3 months of treatment. Perfusion defect persistence rates are higher in defects more proximal to the subsegment level and in people with severe COVID-19, and extended treatment should be considered in these patients.
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Полный текст: Имеется в наличии Коллекция: Международные базы данных база данных: MEDLINE Основная тема: Pulmonary Embolism / COVID-19 Тип исследования: Экспериментальные исследования / Прогностическое исследование Темы: Длинный Ковид Пределы темы: Люди Язык: английский Журнал: Nucl Med Commun Год: 2022 Тип: Статья

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Полный текст: Имеется в наличии Коллекция: Международные базы данных база данных: MEDLINE Основная тема: Pulmonary Embolism / COVID-19 Тип исследования: Экспериментальные исследования / Прогностическое исследование Темы: Длинный Ковид Пределы темы: Люди Язык: английский Журнал: Nucl Med Commun Год: 2022 Тип: Статья