Maternal weight status and the composition of the human milk microbiome: A scoping review.
PLoS One
; 17(10): e0274950, 2022.
Статья
в английский
| MEDLINE | ID: covidwho-2054351
ABSTRACT
The human milk microbiome is thought to partly contribute to the assembly of the infant gut microbiome, a microbial community with important implications for infant health and development. While obesity has well-established links with the adult gut microbiome, less is known about how it affects the human milk microbiome. In this scoping review, we synthesize the current literature on the microbial composition of human milk by maternal weight status, defined broadly as BMI (prepregnancy and postpartum) and gestational weight gain (GWG). This study followed the a priori protocol published in Prospero (registration # CRD42020165633). We searched the following databases for studies reporting maternal weight status and a characterization of milk microbiota through culture-dependent and culture-independent methods:
MEDLINE, Embase, Web of Science, CINAHL, and Scopus. After screening 6,365 studies, we found 20 longitudinal and cross-sectional studies investigating associations between maternal weight status and the composition of the milk microbiome. While some studies reported no associations, many others reported that women with a pre-pregnancy or postpartum BMI characterized as overweight or obese, or with excessive GWG, had higher abundances of the genus Staphylococcus, lower Bifidobacterium abundance, and lower alpha diversity (within-sample diversity). This review suggests that maternal weight status is minorly associated with the composition of the milk microbiome in various ways. We offer potential explanations for these findings, as well as suggestions for future research.
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
Gastrointestinal Microbiome
/
Gestational Weight Gain
Тип исследования:
Наблюдательное исследование
/
Прогностическое исследование
/
Рандомизированные контролируемые испытания
/
Отзывы
Пределы темы:
Взрослые
/
Женщины
/
Люди
/
Грудные дети
/
Беременность
Язык:
английский
Журнал:
PLoS One
Тематика журнала:
Наука
/
Медицина
Год:
2022
Тип:
Статья
Аффилированная страна:
Journal.pone.0274950
Документы, близкие по теме
MEDLINE
...
LILACS
LIS