Omicron Severe Acute Respiratory Syndrome Coronavirus 2 Neutralization by Immunoglobulin Preparations Manufactured From Plasma Collected in the United States and Europe.
J Infect Dis
; 226(8): 1396-1400, 2022 10 17.
Статья
в английский
| MEDLINE | ID: covidwho-2077785
ABSTRACT
After >2 years of the coronavirus disease 2019 (COVID-19) pandemic, immunoglobulins (IGs) contain highly potent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibodies, based on the large proportion of United States (US) plasma donors who have gone through COVID-19 or vaccination against the virus. Neutralization of Omicron SARS-CoV-2 by antibodies generated after non-Omicron infection or vaccination has been lower though, raising concerns about the potency of IG against this new virus variant. Also, as plasma collected in the US remains the main source of IG, the neutralization of SARS-CoV-2 for plasma collected elsewhere has been less well studied. Here, we confirm Omicron neutralization by US as well as European Union plasma-derived IG lots.
ключевые слова
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
Antibodies, Neutralizing
/
SARS-CoV-2
/
COVID-19
Темы:
Вакцина
/
Варианты
Пределы темы:
Люди
Страна как тема:
Северная Америка
/
Европа
Язык:
английский
Журнал:
J Infect Dis
Год:
2022
Тип:
Статья
Аффилированная страна:
Infdis
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