Real-World Accuracy of a SARS-CoV-2 Rapid Diagnostic Tests in the Republic of Korea.
J Korean Med Sci
; 37(43): e310, 2022 Nov 07.
Статья
в английский
| MEDLINE | ID: covidwho-2109726
ABSTRACT
Antigen rapid diagnostic tests (RDTs) became the most important tool for the diagnosis of the coronavirus disease 2019 (COVID-19), however there have been very few evaluations of the accuracy of the RDTs in actual use. In this study, we investigated the performance accuracy of the RDT, the STANDARD Q COVID-19 Ag (STANDARD Q), in the Republic of Korea. We collected a total of 5,792 results that underwent both RDT and reverse transcription polymerase chain reaction simultaneously, and overall sensitivity and specificity of the STANDARD Q were 57.6% and 99.9%, respectively. With binomial logistic regression analysis, we estimated that about half of the COVID-19 patients with a cycle threshold value of 25 for E and RdRP were RDT-negative. These results suggest that the clinical sensitivity of RDTs against severe acute respiratory syndrome coronavirus 2 is considerably low in a real-world setting, and we recommend that limitations of RDTs should be considered when setting up COVID-19 test strategies.
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Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
SARS-CoV-2
/
COVID-19
Тип исследования:
Диагностическое исследование
/
Экспериментальные исследования
/
Прогностическое исследование
Пределы темы:
Люди
Страна как тема:
Азия
Язык:
английский
Журнал:
J Korean Med Sci
Тематика журнала:
Медицина
Год:
2022
Тип:
Статья
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