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New Onset of Diabetes Mellitus and Associated Factors among COVID-19 Patients in COVID-19 Care Centers, Addis Ababa, Ethiopia 2022.
Sane, Asaminew Habtamu; Mekonnen, Migbar Sibhat; Tsegaw, Melsew Getnet; Zewde, Wuletaw Chane; Mesfin, Edmialem Getahun; Beyene, Hailu Asmare; Ashine, Taye Mezgebu; Tiruneh, Kasie Gebeyehu; Mengistie, Melkie Ambaw.
  • Sane AH; School of Nursing, Institute of Health Science, Jimma University, Jimma, Ethiopia.
  • Mekonnen MS; Department of Nursing, College of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
  • Tsegaw MG; Millennium COVID-19 Care Center, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
  • Zewde WC; Millennium COVID-19 Care Center, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
  • Mesfin EG; Millennium COVID-19 Care Center, Saint Paul's Hospital Millennium Medical College, Addis Ababa, Ethiopia.
  • Beyene HA; School of Nursing, College of Health Science and Medicine, Wolaita Sodo University, Sodo, Ethiopia.
  • Ashine TM; Schools of Nursing, College of Health Science and Medicine, Wachemo University, Hosaena, Ethiopia.
  • Tiruneh KG; Department of Nursing, College of Health Science and Medicine, Dilla University, Dilla, Ethiopia.
  • Mengistie MA; Department of Nursing, Arba Minch College of Health Sciences, Arba Minch, Ethiopia.
J Diabetes Res ; 2022: 9652940, 2022.
Статья в английский | MEDLINE | ID: covidwho-2113176
ABSTRACT

Introduction:

New onset of diabetes mellitus was noted as the commonest comorbidity in the COVID-19 pandemic, which contributed to a worse prognosis. Existing evidence showed that new-onset diabetes is associated with increased mortality compared to nondiabetic and known diabetic patients in the COVID-19 era. SARS-CoV-2 virus can worsen existing diabetes; at the same time, it can trigger new-onset diabetes that eventually worsens patient outcomes. Thus, this study is aimed at determining the prevalence and factors associated with new onset of diabetes mellitus among COVID-19 patients.

Methods:

Institution-based retrospective cross-sectional study design was conducted by reviewing 244 patient's records in the Addis Ababa COVID-19 care center. Descriptive statistics and binary logistic regression were used. During bivariate analysis, variables with p ≤ 0.25 were transferred into multivariate analysis. Adjusted odds ratios to determine the strength and presence of the association with a 95% confidence interval and p value ≤ 0.05 were considered, respectively.

Results:

The mean age of the study participants was 53.2 years with (SD = 13.35). The study findings showed that 31.1% (CI 25.4-37.4) of COVID-19 patients had new onset of diabetes mellitus; of those, 11.8% had type 1 and 88.2% had type 2 diabetes. Being male (aOR = 2.9; 95% CI 1.2, 7.1), family history of hypertension (aOR = 3.7; 95% CI 1.3, 10.5), obesity (aOR = 3.1; 95% CI 1.01, 8.9), having pulmonary embolism (aOR = 0.2; 95% CI 0.06, 0.04), and hyperkalemia (aOR = 9.3; 95% CI 1.8, 47.3) showed statistically significant association with new onset of diabetes mellitus.

Conclusion:

A significant proportion of COVID-19 patients had been diagnosed with new onset of diabetes mellitus, and new-onset type 2 diabetes mellitus is the most common diabetes mellitus type. Being male, obesity, having a pulmonary embolism, family history of hypertension, and hyperkalemia were independently associated with new onset of diabetes mellitus among COVID-19 patients. Therefore, focused interventions need to be strengthened towards the identified factors.
Тема - темы

Полный текст: Имеется в наличии Коллекция: Международные базы данных база данных: MEDLINE Основная тема: Pulmonary Embolism / Diabetes Mellitus, Type 2 / COVID-19 / Hyperkalemia / Hypertension Тип исследования: Наблюдательное исследование / Прогностическое исследование / Рандомизированные контролируемые испытания Темы: Длинный Ковид Пределы темы: Женщины / Люди / Мужчины / Middle aged Страна как тема: Африка Язык: английский Журнал: J Diabetes Res Год: 2022 Тип: Статья Аффилированная страна: 2022

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Полный текст: Имеется в наличии Коллекция: Международные базы данных база данных: MEDLINE Основная тема: Pulmonary Embolism / Diabetes Mellitus, Type 2 / COVID-19 / Hyperkalemia / Hypertension Тип исследования: Наблюдательное исследование / Прогностическое исследование / Рандомизированные контролируемые испытания Темы: Длинный Ковид Пределы темы: Женщины / Люди / Мужчины / Middle aged Страна как тема: Африка Язык: английский Журнал: J Diabetes Res Год: 2022 Тип: Статья Аффилированная страна: 2022