Impact of community asymptomatic rapid antigen testing on covid-19 related hospital admissions: synthetic control study.
BMJ
; 379: e071374, 2022 11 23.
Статья
в английский
| MEDLINE | ID: covidwho-2137584
ABSTRACT
OBJECTIVE:
To analyse the impact of voluntary rapid testing for SARS-CoV-2 antigen in Liverpool city on covid-19 related hospital admissions.DESIGN:
Synthetic control analysis comparing hospital admissions for small areas in the intervention population with a group of control areas weighted to be similar for past covid-19 related hospital admission rates and sociodemographic factors.SETTING:
Liverpool city, UK, 6 November 2020 to 2 January 2021, under the intervention of Covid-SMART (systematic meaningful asymptomatic repeated testing) voluntary, open access supervised self-testing with lateral flow devices, compared with control areas selected from the rest of England. POPULATION General population of Liverpool (n=498 042) and a synthetic control population from the rest of England. MAIN OUTCOMEMEASURE:
Weekly covid-19 related hospital admissions for neighbourhoods in England.RESULTS:
The introduction of community testing was associated with a 43% (95% confidence interval 29% to 57%) reduction (146 (96 to 192) in total) in covid-19 related hospital admissions in Liverpool compared with the synthetic control population (non-adjacent set of neighbourhoods with aggregate trends in covid-19 hospital admissions similar to Liverpool) for the initial period of intensive testing with military assistance in national lockdown from 6 November to 3 December 2020. A 25% (11% to 35%) reduction (239 (104 to 333) in total) was estimated across the overall intervention period (6 November 2020 to 2 January 2021), involving fewer testing centres, before England's national roll-out of community testing, after adjusting for regional differences in tiers of covid-19 restrictions from 3 December 2020 to 2 January 2021.CONCLUSIONS:
The city-wide pilot of community based asymptomatic testing for SARS-CoV-2 was associated with substantially reduced covid-19 related hospital admissions. Large scale asymptomatic rapid testing for SARS-CoV-2 could help reduce transmission and prevent hospital admissions.
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
COVID-19
Тип исследования:
Диагностическое исследование
/
Экспериментальные исследования
/
Наблюдательное исследование
/
Прогностическое исследование
/
Систематический обзор/метаанализ
Пределы темы:
Люди
Язык:
английский
Журнал:
BMJ
Тематика журнала:
Медицина
Год:
2022
Тип:
Статья
Аффилированная страна:
Bmj-2022-071374
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