Innate and adaptive immune response in SARS-CoV-2 infection-Current perspectives
Frontiers in immunology
; 13, 2022.
Статья
в английский
| EuropePMC | ID: covidwho-2157239
ABSTRACT
Coronavirus disease 2019 (COVID-19) has been a global pandemic, caused by a novel coronavirus strain with strong infectivity, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). With the in-depth research, the close relationship between COVID-19 and immune system has been dug out. During the infection, macrophages, dendritic cells, natural killer cells, CD8+ T cells, Th1, Th17, Tfh cells and effector B cells are all involved in the anti-SARS-CoV-2 responses, however, the dysfunctional immune responses will ultimately lead to the excessive inflammation, acute lung injury, even other organ failure. Thus, a detailed understanding of pertinent immune response during COVID-19 will provide insights in predicting disease outcomes and developing appropriate therapeutic approaches. In this review, we mainly clarify the role of immune cells in COVID-19 and the target-vaccine development and treatment.
Search on Google
Коллекция:
Базы данных международных организаций
база данных:
EuropePMC
Язык:
английский
Журнал:
Frontiers in immunology
Год:
2022
Тип:
Статья
Документы, близкие по теме
MEDLINE
...
LILACS
LIS