High flow nasal cannula for acute respiratory failure due to COVID-19 in patients with a 'do-not-intubate' order: A survival analysis.
Clin Respir J
; 17(2): 115-119, 2023 Feb.
Статья
в английский
| MEDLINE | ID: covidwho-2192499
ABSTRACT
INTRODUCTION:
High flow nasal cannula (HFNC) reduces the need for intubation in patients with hypoxaemic acute respiratory failure (ARF), but its added value in patients with severe coronavirus disease 2019 (COVID-19) and a do-not-intubate (DNI) order is unknown. We aimed to assess (variables associated with) survival in these patients. MATERIALS ANDMETHODS:
We described a multicentre retrospective observational cohort study in five hospitals in the Netherlands and assessed the survival in COVID-19 patients with severe acute respiratory failure and a DNI order who were treated with high flow nasal cannula. We also studied variables associated with survival. RESULTS ANDDISCUSSION:
One-third of patients survived after 30 days. Survival was 43.9% in the subgroup of patients with a good WHO performance status and only 16.1% in patients with a poor WHO performance status. Patients who were admitted to the hospital for a longer period prior to HFNC initiation were less likely to survive. HFNC resulted in an increase in ROX values, reflective of improved oxygenation and/or decreased respiratory rate.CONCLUSION:
Our data suggest that a trial of HFNC could be considered to increase chances of survival in patients with ARF due to COVID-19 pneumonitis and a DNI order, especially in those with a good WHO performance status.ключевые слова
Полный текст:
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Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
Respiratory Distress Syndrome
/
Respiratory Insufficiency
/
Noninvasive Ventilation
/
COVID-19
Тип исследования:
Когортное исследование
/
Наблюдательное исследование
/
Прогностическое исследование
/
Рандомизированные контролируемые испытания
Темы:
Длинный Ковид
Пределы темы:
Люди
Язык:
английский
Журнал:
Clin Respir J
Год:
2023
Тип:
Статья
Аффилированная страна:
Crj.13573
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