Using Discarded Facial Tissues to Monitor and Diagnose Viral Respiratory Infections.
Emerg Infect Dis
; 29(3): 511-518, 2023 03.
Статья
в английский
| MEDLINE | ID: covidwho-2242441
ABSTRACT
Molecular biology amplification enables sensitive detection of most respiratory viruses through nasopharyngeal swabbing. We developed an innovative approach to detect viral genomes on used facial tissues. In 2 communities of children, used tissues were collected once weekly for 1 year. Pooled analysis of tissues enabled detection of successive virus circulation in 4 age groups over time and forecasted by several weeks the circulation of influenza in the general population. At the individual level, in a proof-of-concept study of 30 volunteers with influenza-like signs/symptoms, we identified common respiratory viruses. The signals for SARS-CoV-2 obtained in parallel from 15 facial tissues and swab samples were similar and often higher for the tissues (11/15). Individual analysis of tissues offers a noninvasive, sensitive, and affordable alternative to self-sampling without a medical care requirement. Pooled analyses may be used to detect virus spread in specific communities, predict seasonal epidemics, and alert the population to viral infections.
ключевые слова
Полный текст:
Имеется в наличии
Коллекция:
Международные базы данных
база данных:
MEDLINE
Основная тема:
Respiratory Tract Infections
/
Viruses
/
Virus Diseases
/
Influenza, Human
/
COVID-19
Тип исследования:
Диагностическое исследование
/
Экспериментальные исследования
/
Наблюдательное исследование
/
Прогностическое исследование
/
Рандомизированные контролируемые испытания
/
Отзывы
Пределы темы:
Дети
/
Люди
Язык:
английский
Журнал:
Emerg Infect Dis
Тематика журнала:
Инфекционные болезни
Год:
2023
Тип:
Статья
Документы, близкие по теме
MEDLINE
...
LILACS
LIS