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Left ventricular global longitudinal strain as a parameter of mild myocardial dysfunction in athletes after COVID-19 (preprint)
medrxiv; 2023.
Препринт
в английский
| medRxiv | ID: ppzbmed-10.1101.2023.03.14.23287258
ABSTRACT
Background Whether impaired left ventricular (LV) function contributes to persistent cardiopulmonary symptoms or decreased exercise capacity after COVID-19 remains unclear. The aim of this prospective study was to determine differences in LV global longitudinal strain (GLS) between athletes who did not have a history of LV dysfunction but had a positive COVID-19 test (PCAt) and healthy control (CON) athletes and relate them to symptoms during COVID-19. Methods We performed 151 transthoracic echocardiographies in our high-performance laboratory. GLS was determined in four-, two-, and three-chamber views and assessed offline by a blinded investigator in 88 PCAt (35% women) at a median of two months after COVID-19 who trained at least three times per week with more than 20 MET per week and 52 CONs from the German national squad (38% women). Results GLS was significantly lower (GLS -18.53 {+/-}1.94% vs. -19.94{+/-}1.42%, p<0.001) and diastolic function significantly reduced (E/A 1.54{+/-}0.52 vs. 1.66{+/-}0.43, p=0.020; E`l 0.15{+/-}0.04 vs. 0.17{+/-}0.04, p=0.009; E/E'l 5.74{+/-}1.74 vs. 5.22{+/-}1.36, p=0.024) in PCAt. There was no association between GLS and acute symptoms like resting dyspnea, exertional dyspnea during or after COVID-19, palpitations, chest pain or increased resting heart rate. However, there was a trend toward lower GLS in PCAt with subjectively perceived performance limitation (p=0.054). Conclusions In a cohort of athletes at a median two months after COVID-19, significantly lower GLS and diastolic function were observed, suggesting mild myocardial dysfunction. GLS could be used as a screening element during return-to-sport examinations.
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Препринты
база данных:
medRxiv
Основная тема:
Sprains and Strains
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Chest Pain
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Ventricular Dysfunction, Left
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Dyspnea
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COVID-19
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Cardiomyopathies
Язык:
английский
Год:
2023
Тип:
Препринт
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