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Understanding barriers to effective management of influenza outbreaks by residential aged care facilities.

Author(s): Huhtinen, Essi; Quinn, Emma; Hess, Isabel; Najjar, Zeina; Gupta, Leena
Source: Australas J Ageing;38(1): 60-63, 2019 Mar.
MEDLINE - International Database for Medical Literature PMID: 30537166
Abstract: OBJECTIVE: To identify the perceived barriers to the implementation of the Australian national guidelines on influenza outbreak management with Sydney Local Health District (SLHD) residential aged care facility (RACF) staff. METHODS: All SLHD RACFs were invited to participate in a telephone interview. The questionnaire collected information about demographic characteristics and participants' level of agreement with statements regarding perceived barriers to implementing the national guideli (more)

The Effect of Individual Movements and Interventions on the Spread of Influenza in Long-Term Care Facilities.

Author(s): Najafi, Mehdi; Laskowski, Marek; de Boer, Pieter T; Williams, Evelyn; Chit, Ayman; Moghadas, Seyed M
Source: Med Decis Making;37(8): 871-881, 2017 11.
MEDLINE - International Database for Medical Literature PMID: 28538110
Abstract: BACKGROUND: Nosocomial influenza poses a serious risk among residents of long-term care facilities (LTCFs). OBJECTIVE: We sought to evaluate the effect of resident and staff movements and contact patterns on the outcomes of various intervention strategies for influenza control in an LTCF. METHODS: We collected contact frequency data in Canada's largest veterans' LTCF by enroling residents and staff into a study that tracked their movements through wireless tags and signal receivers. We anal (more)

What Transmission Precautions Best Control Influenza Spread in a Hospital?

Author(s): Blanco, Natalia; Eisenberg, Marisa C; Stillwell, Terri; Foxman, Betsy
Source: Am J Epidemiol;183(11): 1045-54, 2016 06 01.
MEDLINE - International Database for Medical Literature PMID: 27188950
Abstract: Influenza is a significant problem within hospitals, leading to extended hospital stays, excess morbidity and mortality, and economic loss. Prevention and control strategies are generally "bundled"; therefore, the individual effects of particular strategies and the value of combined strategies cannot be determined directly, making it difficult to discern the optimal strategy. To quantify the individual and joint effectiveness of several known influenza infection control measures used in gen (more)

Assessing the Role of Voluntary Self-Isolation in the Control of Pandemic Influenza Using a Household Epidemic Model.

Author(s): Zhang, Qingxia; Wang, Dingcheng
Source: Int J Environ Res Public Health;12(8): 9750-67, 2015 Aug 18.
MEDLINE - International Database for Medical Literature PMID: 26295248
Abstract: In the absence of effective vaccines, antiviral drugs and personal protective measures, such as voluntary self-isolation, have been a part of preparedness plans for the next influenza pandemic. We used a household model to assess the effect of voluntary self-isolation on outbreak control when antiviral drugs are not provided sufficiently early. We found that the early initiation of voluntary self-isolation can overcome the negative effects caused by a delay in antiviral drug distribution wh (more)

Evidence compendium and advice on social distancing and other related measures for response to an influenza pandemic.

Author(s): Rashid, Harunor; Ridda, Iman; King, Catherine; Begun, Matthew; Tekin, Hatice; Wood, James G; Booy, Robert
Source: Paediatr Respir Rev;16(2): 119-26, 2015 Mar.
MEDLINE - International Database for Medical Literature PMID: 24630149
Abstract: The role of social distancing measures in mitigating pandemic influenza is not precisely understood. To this end, we have conducted a systematised review, particularly in light of the 2009 pandemic influenza, to better inform the role of social distancing measures against pandemic influenza. Articles were identified from relevant databases and the data were synthesised to provide evidence on the role of school or work place-based interventions, case-based distancing (self-isolation, quarant (more)

Antiviral prophylaxis and isolation for the control of pandemic influenza.

Author(s): Zhang, Qingxia; Wang, Dingcheng
Source: Int J Environ Res Public Health;11(8): 7690-712, 2014 Jul 31.
MEDLINE - International Database for Medical Literature PMID: 25089775
Abstract: Before effective vaccines become available, antiviral drugs are considered as the major control strategies for a pandemic influenza. However, perhaps such control strategies can be severely hindered by the low-efficacy of antiviral drugs. For this reason, using antiviral drugs and an isolation strategy is included in our study. A compartmental model that allows for imported exposed individuals and asymptomatic cases is used to evaluate the effectiveness of control strategies via antiviral p (more)

Health and economic benefits of early vaccination and nonpharmaceutical interventions for a human influenza A (H7N9) pandemic: a modeling study.

Author(s): Khazeni, Nayer; Hutton, David W; Collins, Cassandra I F; Garber, Alan M; Owens, Douglas K
Source: Ann Intern Med;160(10): 684-94, 2014 May 20.
MEDLINE - International Database for Medical Literature PMID: 24842415
Abstract: BACKGROUND: Vaccination for the 2009 pandemic did not occur until late in the outbreak, which limited its benefits. Influenza A (H7N9) is causing increasing morbidity and mortality in China, and researchers have modified the A (H5N1) virus to transmit via aerosol, which again heightens concerns about pandemic influenza preparedness. OBJECTIVE: To determine how quickly vaccination should be completed to reduce infections, deaths, and health care costs in a pandemic with characteristics simil (more)

Optimized strategy for the control and prevention of newly emerging influenza revealed by the spread dynamics model.

Author(s): Zhang, Wen-Dou; Zu, Zheng-Hu; Xu, Qing; Xu, Zhi-Jing; Liu, Jin-Jie; Zheng, Tao
Source: PLoS One;9(1): e84694, 2014.
MEDLINE - International Database for Medical Literature PMID: 24392151
Abstract: No matching vaccine is immediately available when a novel influenza strain breaks out. Several nonvaccine-related strategies must be employed to control an influenza epidemic, including antiviral treatment, patient isolation, and immigration detection. This paper presents the development and application of two regional dynamic models of influenza with Pontryagin's Maximum Principle to determine the optimal control strategies for an epidemic and the corresponding minimum antiviral stockpiles (more)

Optimal strategies of social distancing and vaccination against seasonal influenza.

Author(s): Shim, Eunha
Source: Math Biosci Eng;10(5-6): 1615-34, 2013.
MEDLINE - International Database for Medical Literature PMID: 24245639
Abstract: Optimal control strategies for controlling seasonal influenza transmission in the US are of high interest, because of the significant epidemiological and economic burden of influenza. To evaluate optimal strategies of vaccination and social distancing, we used an age-structured dynamic model of seasonal influenza. We applied optimal control theory to identify the best way of reducing morbidity and mortality at a minimal cost. In combination with the Pontryagins maximum principle, we calcula (more)

Selecting nonpharmaceutical interventions for influenza.

Author(s): Jones, Rachael M; Adida, Elodie
Source: Risk Anal;33(8): 1473-88, 2013 Aug.
MEDLINE - International Database for Medical Literature PMID: 23231621
Abstract: Models of influenza transmission have focused on the ability of vaccination, antiviral therapy, and social distancing strategies to mitigate epidemics. Influenza transmission, however, may also be interrupted by hygiene interventions such as frequent hand washing and wearing masks or respirators. We apply a model of influenza disease transmission that incorporates hygiene and social distancing interventions. The model describes population mixing as a Poisson process, and the probability of (more)

Estimating the value of containment strategies in delaying the arrival time of an influenza pandemic: a case study of travel restriction and patient isolation.

Author(s): Wang, Lin; Zhang, Yan; Huang, Tianyi; Li, Xiang
Source: Phys Rev E Stat Nonlin Soft Matter Phys;86(3 Pt 1): 032901, 2012 Sep.
MEDLINE - International Database for Medical Literature PMID: 23030969
Abstract: With a simple phenomenological metapopulation model, which characterizes the invasion process of an influenza pandemic from a source to a subpopulation at risk, we compare the efficiency of inter- and intrapopulation interventions in delaying the arrival of an influenza pandemic. We take travel restriction and patient isolation as examples, since in reality they are typical control measures implemented at the inter- and intrapopulation levels, respectively. We find that the intrapopulation (more)

On the roads to H1N1 pandemic era: drive safe and fearless using colour-coded masks.

Author(s): Shahid, M
Source: Asian Pac J Trop Med;5(4): 333-4, 2012 Apr.
MEDLINE - International Database for Medical Literature PMID: 22449531
Abstract: Notwithstanding the end of 2009 H1N1 pandemic, the threat for its revisit still persists and WHO has warned to remain vigilant. During that time the situation was more panicky than fatal. In this article, a suggestion to minimize the panic is provided by the usage of colour-coded masks and is proposed hereby as a "population segregation" approach in case of the revisit of H1N1 or similar threatening respiratory viral infections.
Results  1-12 de 56