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Resultados  1-12 de 4.241

Identification of SARS-CoV-2 and additional respiratory pathogens cases under the investigation of COVID-19 initial phase in a Brazilian reference laboratory

Autor(es): Laboratório de Vírus Respiratórios e do SarampoMatos, Aline da Rocha; Laboratório de Vírus Respiratórios e do SarampoMotta, Fernando Couto; Laboratório de Vírus Respiratórios e do SarampoCaetano, Braulia Costa; Laboratório de Vírus Respiratórios e do SarampoOgrzewalska, Maria; Laboratório de Vírus Respiratórios e do SarampoGarcia, Cristiana Couto; Laboratório de Vírus Respiratórios e do SarampoLopes, Jonathan Christian Oliveira; Laboratório de Vírus Respiratórios e do SarampoMiranda, Milene; Coordenação-Geral de LaboratóriosLivorati, Miriam Teresinha Furlam Prando; Coordenação-Geral de LaboratóriosAbreu, André; Laboratório de Vírus Respiratórios e do SarampoBrown, David; Laboratório de Vírus Respiratórios e do SarampoSiqueira, Marilda Mendonça
Fonte: Mem. Inst. Oswaldo Cruz;115: e200232, 2020. tab
LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde ID: 1135221
Resumo: Coronavirus disease 2019 (COVID-19) surveillance, in Brazil, initiated shortly after its description, in China. Our aim was to detect severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and additional pathogens in samples from the initial phase of the outbreak in Brazil, from late February to late March. From 707 samples analysed, 29 (4.1%) were SARS-CoV-2 positive. Fever and cough were their most prevalent symptoms. Co-detection of rhinovirus was observed in 2 (6.9%) cases. Additi (mais)

Virological and Epidemiological Situation in the Influenza Epidemic Seasons 2016/2017 and 2017/2018 in Poland.

Autor(es): Hallmann-Szelinska, E; Luniewska, K; Szymanski, K; Kowalczyk, D; Salamatin, R; Masny, A; Brydak, L B
Fonte: Adv Exp Med Biol;1251: 107-113, 2020.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31832902
Resumo: The World Health Organization estimates that influenza virus infects 3-5 million people worldwide every year, of whom 290,000 to 650,000 die. In the 2016/2017 epidemic season in Poland, the incidence of influenza was 1,692 per 100,000 population. The influenza A virus, subtype A/H3N2/, was the predominant one in that season. However, in the most recent 2017/2018 epidemic season, the incidence exceeded 1,782 per 100,000 already by August of 2018. In this season, influenza B virus predominate (mais)

Validation of the Seegene RV15 multiplex PCR for the detection of influenza A subtypes and influenza B lineages during national influenza surveillance in hospitalized adults.

Autor(es): LeBlanc, J J; ElSherif, M; Mulpuru, S; Warhuus, M; Ambrose, A; Andrew, M; Boivin, G; Bowie, W; Chit, A; Dos Santos, G; Green, K; Halperin, S A; Hatchette, T F; Ibarguchi, B; Johnstone, J; Katz, K; Langley, J M; Lagacé-Wiens, P; Loeb, M; Lund, A; MacKinnon-Cameron, D; McCarthy, A; McElhaney, J E; McGeer, A; Poirier, A; Powis, J; Richardson, D; Semret, M; Shinde, V; Smyth, D; Trottier, S; Valiquette, L; Webster, D; Ye, L; McNeil, S A
Fonte: J Med Microbiol;69(2): 256-264, 2020 Feb.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31264957
Resumo: Background. The Serious Outcomes Surveillance Network of the Canadian Immunization Research Network (CIRN SOS) has been performing active influenza surveillance since 2009 ( identifier: NCT01517191). Influenza A and B viruses are identified and characterized using real-time reverse-transcriptase polymerase chain reaction (RT-PCR), and multiplex testing has been performed on a subset of patients to identify other respiratory virus aetiologies. Since both methods can identif (mais)

Antiviral activities of extremophilic actinomycetes extracts from Kazakhstan's unique ecosystems against influenza viruses and paramyxoviruses.

Autor(es): Berezin, Vladimir; Abdukhakimova, Diyora; Trenozhnikova, Lyudmila; Bogoyavlenskiy, Andrey; Turmagambetova, Aizhan; Issanov, Alpamys; Azizan, Azliyati
Fonte: Virol J;16(1): 150, 2019 12 02.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31791359
Resumo: BACKGROUND: Commercially available antiviral drugs, when used in the treatment of viral infections, do not always result in success. This is an urgent problem currently that needs to be addressed because several viruses including influenza and paramyxoviruses are acquiring multi-drug resistance. A potential solution for this emerging issue is to create new antiviral drugs from available compounds of natural products. It is known that the majority of drugs have been developed using compounds (mais)

Biotinylated Single-Domain Antibody-Based Blocking ELISA for Detection of Antibodies Against Swine Influenza Virus.

Autor(es): Du, Taofeng; Zhu, Guang; Wu, Xiaoping; Fang, Junyang; Zhou, En-Min
Fonte: Int J Nanomedicine;14: 9337-9349, 2019.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31819435
Resumo: Background: Enzyme-linked immunosorbent assay (ELISA) is a common method for diagnosing swine influenza. However, the production of classical antibodies is both costly and time-consuming. As a promising alternative diagnostic tool, single-domain antibodies (sdAbs) offer the advantages of simpler and faster generation, good stability and solubility, and high affinity and specificity. Methods: Phage display technology was used to isolate sdAbs against the SIV-NP protein from a camel VHH libra (mais)

Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the "von Magnus effect".

Autor(es): Tapia, Felipe; Wohlfarth, Daniel; Sandig, Volker; Jordan, Ingo; Genzel, Yvonne; Reichl, Udo
Fonte: PLoS One;14(11): e0224317, 2019.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31689309
Resumo: Continuous cell culture-based influenza vaccine production could significantly reduce footprint and manufacturing costs compared to current batch processing. However, yields of influenza virus in continuous mode can be affected by oscillations in virus titers caused by periodic accumulation of defective interfering particles. The generation of such particles has also been observed previously in cascades of continuous stirred tank reactors (CSTRs) and is known as the "von Magnus effect". To (mais)

Spectrum of clinical and radiographic findings in patients with diagnosis of H1N1 and correlation with clinical severity.

Autor(es): Schoen, Karla; Horvat, Natally; Guerreiro, Nicolau F C; de Castro, Isac; de Giassi, Karina S
Fonte: BMC Infect Dis;19(1): 964, 2019 Nov 12.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31718571
Resumo: BACKGROUND: The aim of this study was to evaluate the correlation between clinical and imaging findings with a worse clinical outcome in patients with a confirmed diagnosis of H1N1 influenza A virus. METHODS: Patients with a positive viral test for influenza A H1N1 in 2016 and chest radiography (CR) and/or computed tomography (CT) results had clinical and imaging data reviewed. Hospitalization, admission to the intensive care unit or death were defined as worse clinical outcomes. The associ (mais)

Acute Influenza A virus outbreak in an enzootic infected sow herd: Impact on viral dynamics, genetic and antigenic variability and effect of maternally derived antibodies and vaccination.

Autor(es): Ryt-Hansen, Pia; Pedersen, Anders Gorm; Larsen, Inge; Krog, Jesper Schak; Kristensen, Charlotte Sonne; Larsen, Lars Erik
Fonte: PLoS One;14(11): e0224854, 2019.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31725751
Resumo: Influenza A virus (IAV) is a highly contagious pathogen in pigs. Swine IAV (swIAV) infection causes respiratory disease and is thereby a challenge for animal health, animal welfare and the production economy. In Europe, the most widespread strategy for controlling swIAV is implementation of sow vaccination programs, to secure delivery of protective maternally derived antibodies (MDAs) to the newborn piglets. In this study we report a unique case, where a persistently swIAV (A/sw/Denmark/P5U (mais)

Post-pandemic influenza A/H1N1pdm09 is associated with more severe outcomes than A/H3N2 and other respiratory viruses in adult hospitalisations.

Autor(es): Minney-Smith, C A; Selvey, L A; Levy, A; Smith, D W
Fonte: Epidemiol Infect;147: e310, 2019 11 28.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31775940
Resumo: This study compares the frequency and severity of influenza A/H1N1pdm09 (A/H1), influenza A/H3N2 (A/H3) and other respiratory virus infections in hospitalised patients. Data from 17 332 adult hospitalised patients admitted to Sir Charles Gairdner Hospital, Perth, Western Australia, with a respiratory illness between 2012 and 2015 were linked with data containing reverse transcription polymerase chain reaction results for respiratory viruses including A/H1, A/H3, influenza B, human metapneum (mais)

Nanoantenna enhanced terahertz interaction of biomolecules.

Autor(es): Adak, Subham; Tripathi, Laxmi Narayan
Fonte: Analyst;144(21): 6172-6192, 2019 Oct 22.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31584044
Resumo: Terahertz time-domain spectroscopy (THz-TDS) is a non-invasive, non-contact and label-free technique for biological and chemical sensing as THz-spectra are less energetic and lie in the characteristic vibration frequency regime of proteins and DNA molecules. However, THz-TDS is less sensitive for the detection of micro-organisms of size equal to or less than λ/100 (where, λ is the wavelength of the incident THz wave), and molecules in extremely low concentration solutions (like, a (mais)

Update: Influenza Activity - United States and Worldwide, May 19-September 28, 2019, and Composition of the 2020 Southern Hemisphere Influenza Vaccine.

Autor(es): Epperson, Scott; Davis, C Todd; Brammer, Lynnette; Abd Elal, Anwar Isa; Ajayi, Noreen; Barnes, John; Budd, Alicia P; Burns, Erin; Daly, Peter; Dugan, Vivien G; Fry, Alicia M; Jang, Yunho; Johnson, Sara Jo; Kniss, Krista; Kondor, Rebecca; Grohskopf, Lisa A; Gubareva, Larisa; Merced-Morales, Angiezel; Sessions, Wendy; Stevens, James; Wentworth, David E; Xu, Xiyan; Jernigan, Daniel
Fonte: MMWR Morb Mortal Wkly Rep;68(40): 880-884, 2019 Oct 11.
MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 31600182
Resumo: During May 19-September 28, 2019,* low levels of influenza activity were reported in the United States, with cocirculation of influenza A and influenza B viruses. In the Southern Hemisphere seasonal influenza viruses circulated widely, with influenza A(H3) predominating in many regions; however, influenza A(H1N1)pdm09 and influenza B viruses were predominant in some countries. In late September, the World Health Organization (WHO) recommended components for the 2020 Southern Hemisphere infl (mais)
Resultados  1-12 de 4.241