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Resultados 1-12 de 2.969

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Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection/ Achados iniciais na radiografia de tórax em uma população pediátrica com diagnóstico de infecção viral por H1N1

Autor(es): Adôrno, Isa Félix; Tibana, Tiago Kojun; Santos, Rômulo Florêncio Tristão; Leão, Victor Machado Mendes; Brustoloni, Yvone Maia; Silva, Pedro Augusto Ignácio; Ferreira, Marco Antônio; Nunes, Thiago Franchi

Fonte: Radiol. bras;52(2): 78-84, Mar.-Apr. 2019. tab, graf

LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde ID: 1002993

LILACS Express

Resumo: Abstract Objective: To evaluate chest X-ray findings in pediatric patients diagnosed with influenza A (H1N1) virus infection. Materials and Methods: We retrospectively reviewed chest X-ray findings in 17 cases of pulmonary infection with the H1N1 virus (in 7 males and 10 females) examined between 2012 and 2016. The mean age of the patients was 14 months (range, 2-89 months). The diagnosis was established on the basis of clinical and radiographic criteria, and the virus was detected by pol (mais) ymerase chain reaction. The radiographic findings were categorized by type/pattern of opacity and by lung zone. The patients were divided into two groups: those not requiring ventilatory support; and those requiring ventilatory support or evolving to death. Results: The abnormality most often seen on chest X-rays was that of peribronchovascular opacities, the majority of which affected less than 25% of the lung, the involvement being bilateral and asymmetric. The lung zone most frequently involved was the middle third, with central and peripheral distribution, without pleural effusion. There was a statistically significant difference between the groups in terms of the symmetry of pulmonary involvement, asymmetric findings predominating in the group that required ventilatory support (p = 0.029). Conclusion: In pediatric patients with H1N1 virus infection, the main alterations on the initial chest X-rays are peribronchovascular opacities, nonspecific alveolar opacities, and consolidations. Although the definitive diagnosis of H1N1 virus infection cannot be made on the basis of imaging characteristics alone, using a combination of clinical and radiographic findings can substantially improve the diagnostic accuracy.

Resumo Objetivo: Avaliar os achados na radiografia de tórax de pacientes com diagnóstico de infecção pelo vírus influenza. Materiais e Métodos: Revisamos, retrospectivamente, os achados na radiografia de tórax de 17 casos de infecção pulmonar pelo vírus influenza (7 do sexo masculino e 10 do sexo feminino; idade média de 14 meses, variação de 2 a 89 meses). Os pacientes foram examinados entre 2012 e 2016 e o diagnóstico foi estabelecido por critérios clinicorradiológicos e detecção do vírus por reação em cadeia de polimerase. Os achados radiológicos foram caracterizados por tipo e padrão de opacidade e distribuição por zonas pulmonares. A população estudada foi dividida em dois grupos: sem suporte ventilatório e com suporte ventilatório e/ou óbito. Resultados: A anormalidade encontrada com maior frequência na radiografia de tórax foram as marcas peribroncovasculares, a maioria delas com extensão menor de 25% do pulmão, envolvimento bilateral e assimétrico. A região mais frequentemente envolvida foi o terço médio, com distribuição central e periférica e ausência de derrame pleural. Houve diferença estatisticamente significante na simetria do envolvimento pulmonar, entre os grupos, havendo preponderância de achado assimétrico (p = 0,029) no grupo que necessitou de suporte ventilatório. Conclusão: Pacientes pediátricos com infecção pelo H1N1 apresentam como alterações principais na radiografia do tórax inicial marcas peribroncovasculares, opacidades alveolares inespecíficas e consolidações. Embora o diagnóstico definitivo não possa ser feito com base em imagens características isoladas, uma combinação dos achados clínicos e radiográficos pode melhorar substancialmente a acurácia do diagnóstico nessa doença.

Link(s):

http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-39842019000200078

InfeccioÌn respiratoria por adenovirus en pediatriÌa: de ayer a hoy/ Adenovirus pediatric respiratory infection: past and present

Autor(es): Avendaño C, Luis F

Fonte: Neumol. pediátr. (En línea);14(1): 12-18, abr. 2019. ilus, tab

LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde ID: 995613

Resumo: Acute respiratory infections represent a world pediatric health burden. RSV, influenza and adenoviruses are among the most frequent causative agents. Adenoviruses usually produce upper respiratory infections, but they can be responsible for acute lower respiratory infection in children with severe clinical outcome. It is necessary a special clinical and epidemiological organization to avoid nosocomial adenovirus local outbreaks. Rapid diagnose, done by immunofluorescence assay and PCR, indi (mais)

Assunto(s): Humanos Lactente Criança Infecções Respiratórias/diagnóstico Infecções Respiratórias/etiologia Infecções por Adenovirus Humanos/diagnóstico Infecções por Adenovirus Humanos/etiologia Infecções Respiratórias/terapia Infecções Respiratórias/epidemiologia Infecções Respiratórias/virologia Infecções por Adenovirus Humanos/terapia Infecções por Adenovirus Humanos/epidemiologia Adenovírus Humanos/patogenicidade

Link(s):

http://www.neumologia-pediatrica.cl/wp-content/uploads/2019/05/3.pdf

Influenza A. Manejo ambulatorio/ Influenza A. Ambulatory management

Autor(es): Nogales, José Alejandro

Fonte: Rev. Asoc. Méd. Argent;132(1): 28-32, Mar. 2019. tab, graf

LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde ID: 1010018

Resumo: Introducción. La influenza A constituye uno de los principales problemas de salud que enfrenta la humanidad.El manejo clínico ambulatorio usando el protocolo de oseltamivir y saturomería permite realizar una práctica evaluación. Objetivo. Evaluar resultados usando protocolo de oseltamivir y saturometría en atención médica ambulatoria y emergencias en pacientes con influenza A. Métodos. Realizar un estudio clínico experimental aleatorio en pacientes con influenza A, usando protocol (mais)

Link(s):

https://www.ama-med.org.ar/uploads_archivos/1601/Rev-1-2019-Pag-28-32_Nogales.pdf

Single-Step Detection of the Influenza Virus Hemagglutinin Using Bacterially-Produced Quenchbodies.

Autor(es): Jeong, Hee-Jin; Dong, Jinhua; Ueda, Hiroshi

Fonte: Sensors (Basel);19(1)2018 Dec 23.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30583603

Resumo: We have successfully generated a Quenchbody that enables the detection of the influenza virus hemagglutinin (HA), in a simple and convenient manner. By two-site labeling of the bacterially-produced anti-HA Fab with ATTO520, its fluorescence intensity was increased to 4.4-fold, in the presence of a nanomolar concentration of H1N1 HA. Our results indicate the potential use of this Quenchbody, as a sensor for the simple in situ detection of influenza A virus.

Assunto(s): Glicoproteínas de Hemaglutininação de Vírus da Influenza/isolamento & purificação Fragmentos Fab das Imunoglobulinas/imunologia Vírus da Influenza A Subtipo H1N1/isolamento & purificação Influenza Humana/diagnóstico Anticorpos Anti-Idiotípicos/imunologia Glicoproteínas de Hemaglutininação de Vírus da Influenza/química Glicoproteínas de Hemaglutininação de Vírus da Influenza/imunologia Humanos Fragmentos Fab das Imunoglobulinas/química Vírus da Influenza A Subtipo H1N1/química Vírus da Influenza A Subtipo H1N1/patogenicidade Influenza Humana/imunologia Influenza Humana/virologia

Link(s):

http://dx.doi.org/10.3390/s19010052

99mTc-HMPAO-labeled leukocyte SPECT/CT and transthoracic echocardiography diagnostic value in infective endocarditis.

Autor(es): Holcman, Katarzyna; Szot, Wojciech; Rubis, Pawel; Lesniak-Sobelga, Agata; Hlawaty, Marta; Wisniowska-Smialek, Sylwia; Malecka, Barbara; Zabek, Andrzej; Boczar, Krzysztof; Stepien, Agnieszka; Podolec, Piotr; Kostkiewicz, Magdalena

Fonte: Int J Cardiovasc Imaging;2018 Oct 31.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30382475

Resumo: Infective endocarditis (IE) is a life-threatening disease, establishing a diagnosis is often challenging. The aim of this prospective study was to evaluate and compare the diagnostic performance of the combined use of single photon emission tomography and computed tomography with technetium99m-hexamethylpropyleneamineoxime-labeled leukocytes (99mTc-HMPAO-SPECT/CT) with transthoracic echocardiography (TTE) in patients with suspected IE. We enrolled 40 consecutive patients (12 females, 28 mal (mais)

Link(s):

http://dx.doi.org/10.1186/s12859-018-2408-7

Mobile Fall Risk Assessment Solution for Daily-Life Settings.

Autor(es): Simila, Heidi; Immonen, Milla; Niemirepo, Timo

Fonte: Conf Proc IEEE Eng Med Biol Soc;2018: 1530-1533, 2018 Jul.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30440684

Resumo: Prevention of falls requires accurate means for fall risk assessment in order to identify persons at risk. This paper introduces a novel mobile fall risk assessment solution for daily-life settings. The solution contains an Android application that uses acceleration sensor data received via Bluetooth LE connection. The application guides through a simple walk test, analyzes the acceleration data measured from the acceleration sensor attached to the lower back and gives feedback about the fa (mais)

Link(s):

http://dx.doi.org/10.1109/EMBC.2018.8512856

The temporal dynamics of perceptual and conceptual fluency on recognition memory.

Autor(es): Wang, Wei; Li, Bingbing; Gao, Chuanji; Guo, Chunyan

Fonte: Brain Cogn;127: 1-12, 2018 Nov.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30176534

Resumo: Recognition memory can be driven by both perceptual and conceptual fluency, but when and to what extent they contribute to recognition memory remains an open question. The present study used event-related potentials (ERPs) to investigate the neural correlates of perceptual and conceptual fluency, when they gave rise to recognition. We manipulated the perceptual and conceptual fluency of retrieval cues in the recognition test independently to obtain the effects of different types of fluency. (mais)

Link(s):

http://dx.doi.org/10.1186/s12879-018-3365-5

Biomarker Clinical Trials in Lung Cancer: Design, Logistics, Challenges, and Practical Considerations.

Autor(es): Le-Rademacher, Jennifer; Dahlberg, Suzanne; Lee, J Jack; Adjei, Alex A; Mandrekar, Sumithra J

Fonte: J Thorac Oncol;13(11): 1625-1637, 2018 Nov.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30194034

Resumo: Treatment for lung cancer has evolved in the past 3 decades starting with platinum-based chemotherapy as the standard of care, regardless of histology, in the early 1990s to the current age of biomarker-driven therapy. Consequently, clinical trials in lung cancer have evolved in response to this new shift of paradigm, leading to novel approaches that simultaneously shorten the development process and allow evaluation of multiple patient cohorts. Herein, we provide an overview of the landsca (mais)

Link(s):

http://dx.doi.org/10.1038/s41598-018-31786-8

Does feeding frequency during lactation affect sows' body condition, reproduction and production performance?

Autor(es): Poulopoulou, Ioanna; Eggemann, Anne; Moors, Eva; Lambertz, Christian; Gauly, Matthias

Fonte: Anim Sci J;89(11): 1591-1598, 2018 Nov.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30246330

Resumo: The present study investigated whether a three-times compared to two-times feeding frequency during lactation affects sows' body condition, reproductive performance as well as growth performance of the piglets . In a commercial farm, eight groups (8-10 animals) with a total number of 68 sows were included in the study. During lactation, four groups received feed two times (treatment 2DF) and four groups three times daily (treatment 3DF). Within treatments, sows were classified into young (< (mais)

Link(s):

http://dx.doi.org/10.5578/tt.66122

10.

Adultos con influenza, evolución clínica, costos y grupos relacionados por el diagnóstico, resultados de 4 años. Clínica Dávila. Santiago de Chile/ Adults patients with influenza, clinical evolution, cost and diagnosis related groups, four years results. Clinica Dávila, Santiago, Chile

Autor(es): Maquilón O, César; Munster C, Elizabeth; Tapia P, Cecilia; Antolini T, Mónica; Cabrera V, Sebastián; Arpón F, Paula

Fonte: Rev. chil. enferm. respir;34(2): 102-110, ago. 2018. tab, graf

LILACS - Literatura Latino-Americana e do Caribe em Ciências da Saúde ID: 959414

Resumo: Resumen Introducción: En 2009 la Influenza A H1N1pdm09 provocó en Chile 12.258 casos y 155 muertes. Objetivo: Analizar en adultos egresados de Clínica Dávila con influenza, en 2009, 2010, 2012 y 2014, soporte ventilatorio, costo de hospitalización, Grupos Relacionados por el Diagnóstico (GRD) y letalidad. Material y Método: Estudio descriptivo retrospectivo usando la ficha médica electrónica. Resultados: Egresaron 115.673 adultos, 338 (0,29%) con diagnóstico de Influenza, edad (mais) 56,5 ± 22 años, 59% mujeres, letalidad 4%. Hubo 3 grupos, Grupo 1: sin ningún soporte ventilatorio, 295 pacientes, edad 63 ± 20, estadía 6,6 ± 6,9 días, costo promedio de hospitalización $2.885.261, mediana peso GRD 0,41 (p25 = 0,38 y p75 = 0,62), letalidad 1,01% (3 pacientes). Grupo 2: Ventilación mecánica no invasiva (VMNI), 23 casos, edad 77,1 ± 13, letalidad 22% (5 casos), estadía 16,8 ± 12,4, costo $9.245.242, GRD 0,79 (p25 = 0,62 y p75=1,03). Grupo 3: Intubación y ventilación mecánica invasiva (VMI), 20 pacientes, edad 56,4 ± 15, estadía 36,9 ± 41,4, costo $38.681.099, GRD 5,86 (p25 = 5,82 y p75 = 5,86) y letalidad 30% (6 pacientes). Los GRD grupo VMI versus grupo VMNI y ningún soporte fueron diferentes (p < 0,0001 y p < 0,0001 respectivamente). La letalidad por influenza el 2014 fue de 8,5%, mientras que en los años 2012, 2010 y 2009 fue 1,5%, 3% y 2,5% respectivamente. La mediana de edad el año 2009 fue 37,5 años, menor que la de los otros años (p < 0,0001). Conclusiones: En 2009 los pacientes fueron más jóvenes, la necesidad de soporte ventilatorio provocó un peso GRD, estadía, costo y letalidad mayores que aquellos que no lo requirieron.

Introduction: In 2009 Influenza A H1N1pdm09 caused in Chile 12,258 cases and 155 deaths. Objective: To analyze ventilatory support, cost of hospitalization, Diagnosis Related Groups (DRG) and lethality in adults patients with influenza discharged from our institution, during 2009, 2010, 2012 and 2014. Patients and Method: Retrospective descriptive study using electronic medical records. Results: 115,673 adults were discharged, 338 (0.29%) with diagnosis of Influenza, age 56.5 ± 22 yr.o., 59% women, lethality 4%. There were 3 groups, Group 1: without any ventilatory support, 295 patients, age 63 ± 20, stay 6.6 ± 6.9 days, average cost of hospitalization 2,885,261 clp, medium weight DRG 0.41 (p25 = 0.38) andp75 = 0.62), lethality 1.01% (3 patients). Group 2: Non-invasive mechanical ventilation (NIMV), 23 cases, age 77.1 ± 13, lethality 22% (5 cases), stay 16.8 ± 12.4, cost 9,245,242 clp, DRG 0.79 (p25 = 0.62 and p75 = 1.03). Group 3: Intubation and invasive mechanical ventilation (IMV), 20 patients, age 56.4 ± 15, stay 36.9 ± 41.4, cost 38.681.099 clp, DRG 5.86 (p25 = 5.82 and p75 = 5,86) and lethality 30% (6 patients). The DRG group VMI versus group VMNI and no support were different (p < 0.0001 and p < 0.0001 respectively). The lethality for influenza in 2014 was 8.5%, while in 2012, 2010 and 2009 it was 1.5%, 3% and 2.5% respectively. The median age in 2009 was 37.5 yr.o significantly minor, than the other years (p < 0.0001). Conclusions: In 2009 the patients were younger, the need for ventilatory support led to a higher DRG weight, stay, cost and lethality than those who did not require it.

Assunto(s): Humanos Masculino Feminino Adolescente Adulto Pessoa de Meia-Idade Respiração Artificial/métodos Grupos Diagnósticos Relacionados Influenza Humana/diagnóstico Influenza Humana/virologia Respiração Artificial/instrumentação Evolução Clínica Chile/epidemiologia Estudos Retrospectivos Custos Hospitalares/estatística & dados numéricos Influenza Humana/mortalidade Registros Eletrônicos de Saúde Ventilação não Invasiva Hospitalização

Link(s):

http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-73482018000200102

11.

Surviving, not thriving: a qualitative analysis of parents' perceptions of physical activity participation for rurally residing children with a disability.

Autor(es): Robinson, Timothy; Wakely, Luke; Marquez, Jodie; Rae, Kym

Fonte: Rural Remote Health;18(3): 4536, 2018 08.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 30138036

Resumo: INTRODUCTION: Preliminary research suggests that rurally residing children with a disability seldom participate in the recommended 60 minutes of moderate-to-vigorous physical activity per day and face multiple barriers to participation. The purpose of this study was to explore parents' perceptions of physical activity participation of rurally residing children with a disability, including barriers and any factors that may facilitate their participation. METHODS: Participants were parents or (mais)

Link(s):

http://dx.doi.org/10.15585/mmwr.mm6733a4

12.

Biologic prescribing decisions following serious infection: results from the British Society for Rheumatology Biologics Register-Rheumatoid Arthritis.

Autor(es): Subesinghe, Sujith; Rutherford, Andrew Ian; Byng-Maddick, Rachel; Hyrich, Kimme Leanne; Galloway, James Benjamin

Fonte: Rheumatology (Oxford);57(12): 2096-2100, 2018 Dec 01.

MEDLINE - Literatura Internacional em Ciências da Saúde PMID: 29986108

Resumo: Objectives: To establish whether the decision to stop, continue or switch TNF inhibitor (TNFi) therapy to a biologic drug with an alternative mode of action following a serious infection (SI) impacts upon the risk of recurrent SI in patients with RA. Methods: Patients recruited to the British Society for Rheumatology Biologics Register-RA with at least one episode of SI while on TNFi were included. The biologic treatment decision following SI was considered. A multivariable adjusted Cox pro (mais)

Link(s):

http://dx.doi.org/10.1055/s-0038-1666975

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Pesquisa | Influenza A (H1N1)

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Initial chest X-ray findings in pediatric patients diagnosed with H1N1 virus infection/ Achados iniciais na radiografia de tórax em uma população pediátrica com diagnóstico de infecção viral por H1N1

InfeccioÌn respiratoria por adenovirus en pediatriÌa: de ayer a hoy/ Adenovirus pediatric respiratory infection: past and present

Influenza A. Manejo ambulatorio/ Influenza A. Ambulatory management

Single-Step Detection of the Influenza Virus Hemagglutinin Using Bacterially-Produced Quenchbodies.

99mTc-HMPAO-labeled leukocyte SPECT/CT and transthoracic echocardiography diagnostic value in infective endocarditis.

Mobile Fall Risk Assessment Solution for Daily-Life Settings.

The temporal dynamics of perceptual and conceptual fluency on recognition memory.

Biomarker Clinical Trials in Lung Cancer: Design, Logistics, Challenges, and Practical Considerations.

Does feeding frequency during lactation affect sows' body condition, reproduction and production performance?

Adultos con influenza, evolución clínica, costos y grupos relacionados por el diagnóstico, resultados de 4 años. Clínica Dávila. Santiago de Chile/ Adults patients with influenza, clinical evolution, cost and diagnosis related groups, four years results. Clinica Dávila, Santiago, Chile

Surviving, not thriving: a qualitative analysis of parents' perceptions of physical activity participation for rurally residing children with a disability.

Biologic prescribing decisions following serious infection: results from the British Society for Rheumatology Biologics Register-Rheumatoid Arthritis.