Your browser doesn't support javascript.

Biblioteca Virtual em Saúde

Haiti

Home > Pesquisa > ()
XML
Imprimir Exportar

Formato de exportação:

Exportar

Email
Adicionar mais destinatários
| |

Building endocytic pits without clathrin.

Johannes, Ludger; Parton, Robert G; Bassereau, Patricia; Mayor, Satyajit.
Nat Rev Mol Cell Biol ; 16(5): 311-21, 2015 05.
Artigo Inglês | MEDLINE | ID: mdl-25857812
How endocytic pits are built in clathrin- and caveolin-independent endocytosis still remains poorly understood. Recent insight suggests that different forms of clathrin-independent endocytosis might involve the actin-driven focusing of membrane constituents, the lectin-glycosphingolipid-dependent construction of endocytic nanoenvironments, and Bin-Amphiphysin-Rvs (BAR) domain proteins serving as scaffolding modules. We discuss the need for different types of internalization processes in the context of diverse cellular functions, the existence of clathrin-independent mechanisms of cargo recruitment and membrane bending from a biological and physical perspective, and finally propose a generic scheme for the formation of clathrin-independent endocytic pits.