ABSTRACT
Nail fold is one of the most accessible sites for studying changes in the microcirculation in various microangiopathies. The characterization of changes in microvasculature can provide useful clues towards the diagnosis and prognosis of a disease. The diagnostic utility of nail fold capillaroscopy has improved and expanded over the past couple of decades. Beyond connective tissue diseases, it is now explored for its role in various systemic and dermatological diseases. Incorporation of nail-fold capillaroscopy in the diagnostic criteria of systemic sclerosis has generated interest among dermatologists. The current review is aimed at providing knowledge about nail-fold capillaroscopy to dermatologists. For the purpose of review, a PubMed search was done using the keywords "nail fold capillaries" and "nail fold capillaroscopy". All the articles were retrieved and classified into reviews and clinical studies of various types. The final data were then analyzed and presented in a narrative fashion.
Subject(s)
Microscopic Angioscopy , Scleroderma, Systemic , Capillaries , Dermatologists , Humans , Nails/blood supply , Scleroderma, Systemic/diagnosisSubject(s)
Foot Dermatoses/diagnosis , Onychomycosis/diagnosis , Adult , Dermoscopy/methods , Female , Foot Dermatoses/pathology , Humans , Male , Onychomycosis/pathology , Young AdultABSTRACT
BACKGROUND: Nailfold capillaroscopy (NFC) is a convenient method for studying capillary morphology in the proximal nailfold (PNF) and is used for the evaluation of connective tissue and other diseases affecting the microvasculature. However, capillary density and morphological patterns in healthy individuals are largely unknown and this compromises the evaluation of the microvasculature in disease states. OBJECTIVE: To describe and quantify the morphological characteristics of nailfold capillaries in healthy adult Indians. METHODS: A USB 2.0 dermatoscope (Dinolite AM413ZT) with polarizing light was used to study nailfold capillary characteristics in 50 consecutive healthy adult individuals. NFC was performed on all 10 fingers. Images were assessed for both quantitative and qualitative features. RESULTS: The mean capillary density in healthy Indian adults was 7.63 ± 1.12 capillary/mm. Tortuosity (22%), meandering capillaries (14%) and microhemorrhages (14%) were frequently seen in these individuals. LIMITATION: The small sample size limited a conclusive determination of statistically significant differences in NFC findings with respect to gender and age. CONCLUSION: NFC with a USB dermatoscope is a useful technique for studying the PNF capillaries. The normal PNF capillary density in healthy Indian adults was 7.63 ± 1.12 capillary/mm. Capillary alterations such as tortuosity, meandering capillaries and microhemorrhages are seen in a significant number of healthy individuals.
Subject(s)
Capillaries/diagnostic imaging , Nails/blood supply , Nails/diagnostic imaging , Adult , Cross-Sectional Studies , Dermoscopy , Female , Fingers/blood supply , Humans , India , Male , Microscopic Angioscopy , Reference ValuesSubject(s)
Bedbugs , Bites and Stings/etiology , Wheelchairs/parasitology , Animals , Dermoscopy , Entomology , MaleSubject(s)
Alopecia/diagnosis , Eyebrows/pathology , Genetic Diseases, X-Linked/diagnosis , Child , Humans , MaleSubject(s)
Adrenergic beta-Antagonists/administration & dosage , Aortic Coarctation/diagnostic imaging , Aortic Coarctation/drug therapy , Eye Abnormalities/diagnostic imaging , Eye Abnormalities/drug therapy , Neurocutaneous Syndromes/diagnostic imaging , Neurocutaneous Syndromes/drug therapy , Timolol/administration & dosage , Administration, Topical , Female , Follow-Up Studies , Humans , InfantABSTRACT
Onychoscopy refers to the examination of the nail unit using a dermoscope. Since the advent of dermoscopy, attempts have been made to use it for the diagnosis of nail disorders, most commonly pigmented lesions. As of now, onychoscopy has carved out a distinct niche for itself in the diagnostic work up of nail disorders. The nail is capable of mounting only a limited number of reaction patterns to the large number of disorders affecting it. Therefore, simple visual inspection may not be helpful in diagnosing many conditions reliably. Even a nail biopsy may not give a definitive answer every time. Onychoscopy is thus a valuable aid not only in enhancing visible nail features but also in revealing cryptic features of diagnostic value. This review aims to summarize the current level of knowledge about onychoscopic features of various diseases of the nail unit. It also aims to offer practical tips on how to conduct onychoscopy. For the purpose of review, a PubMed search about the indications and results of onychoscopy was done using the keywords "onychoscopy," "nail fold capillaroscopy," "dermoscopy nail" and "dermatoscopy nail." All the articles were retrieved and classified into case reports, reviews and clinical studies. The final data was then analyzed and presented in a narrative fashion.