ABSTRACT
BACKGROUND: Psoriasis is a common disorder worldwide. The prevalence of psoriasis in Egypt, an African country with a Caucasian population, ranges 0.19-3%. Despite this relatively high prevalence of psoriasis, there are no epidemiologic data regarding the burden of associated eye affection. Determining the magnitude of the problem could help in offering better integrated health services. AIM: The purpose of this study was to evaluate eye involvement in a sample of Egyptian psoriatic patients. PATIENTS AND METHODS: This case-control study included 100 patients with psoriasis and 100 age and sex matched healthy controls. Psoriasis extent and severity was graded by psoriasis area and severity index (PASI). Complete ophthalmological examination and tests for dry eye were performed to all subjects. RESULTS: The mean age of the psoriasis group was 50.7 ± 14.3 years. Thirty eight percent of the cases were females. The mean duration of psoriasis was 10.1 ± 7.5 years. Psoriasis patients had more conjunctival injection (n = 40, P = 0.035), more pinguecula (n = 38, P = 0.048) than controls. Ocular surface disease index (OSDI), tear breakup time (TBUT), Schirmer I, and Rose Bengal staining showed statistically significant positive results in the psoriasis group. CONCLUSION: This is the first report on the prevalence of eye comorbidities in Egyptian psoriatic patients. Dry eyes were more common with psoriasis, particularly the erythrodermic type. Other ocular findings were not statistically significantly different except for conjunctival injection and pinguecula.
Subject(s)
Dry Eye Syndromes/diagnosis , Dry Eye Syndromes/epidemiology , Psoriasis/diagnosis , Psoriasis/epidemiology , Adult , Aged , Aged, 80 and over , Case-Control Studies , Egypt/epidemiology , Eye Diseases/diagnosis , Eye Diseases/epidemiology , Female , Humans , Male , Middle Aged , Prevalence , Young AdultABSTRACT
PURPOSE: To determine the prevalence of dry eye in Hansen's disease patients from the "Hospital de Dermatologia Sanitária de Goiânia". METHODS: The sample of the present study included 70 patients with Hansen's disease, from the "Hospital de Dermatologia Sanitária de Goiânia", and 30 controls, from the "Fundação Banco de Olhos de Goiás", both located in Goiânia-GO, Brazil. Ophthalmologic examination and Schirmer I, break-up time (BUT) and rose Bengal staining tests were carried out for all patients in a single evaluation. For the diagnosis of dry eye the Schirmer I equal or less than 5 mm and rose Bengal grade II or III, in at least one eye were considered. RESULTS: Forty-four (63.0%) patients with Hansen's disease were male and 22 (73.3%) controls were female (p=0.001). The mean age of the patients with Hansen's disease was 61.1+/-12.5 years and in the control group, it was 55.7+/-9.6 years. Fifteen (21.4%) patients with Hansen's disease and four (13.3%) controls presented with dry eye diagnosis (p=0.429). The lepromatous type (74.2%) of Hansen's disease was the most prevalent and dry eye (66.7%) was more frequent in this clinical form of the disease. CONCLUSION: The dry eye disease was more prevalent in patients with Hansen's disease, although the difference was not statistically significant.
Subject(s)
Dry Eye Syndromes/epidemiology , Leprosy/epidemiology , Tears/physiology , Adult , Age Factors , Brazil/epidemiology , Case-Control Studies , Chi-Square Distribution , Female , Fluorescent Dyes , Humans , Male , Middle Aged , Prevalence , Rose Bengal , Sex FactorsABSTRACT
OBJETIVO: Determinar a prevalência de olho seco em hansenianos do Hospital de Dermatologia Sanitária de Goiânia. MÉTODOS: A amostra do presente estudo incluiu 70 hansenianos, do Hospital de Dermatologia Sanitária de Goiânia, e 30 controles, da Fundação Banco de Olhos de Goiás, ambos localizados em Goiânia-GO. Foram realizados exame oftalmológico e testes de Schirmer I, "break-up time" (BUT) e rosa bengala em todos estes indivíduos em uma única avaliação. Para o diagnóstico de olho seco foi considerado o teste de Schirmer I menor ou igual a 5 mm e o rosa bengala grau II ou III, em pelo menos um olho. RESULTADOS: Quarenta e quatro (63,0 por cento) hansenianos eram do sexo masculino e 22 (73,3 por cento) controles, do sexo feminino (p=0,001). A idade média dos hansenianos foi de 61,1±12,5 anos e no grupo controle, 55,7±9,6 anos. Quinze (21,4 por cento) hansenianos e quatro (13,3 por cento) controles apresentaram diagnóstico de olho seco (p=0,429). A forma virchowiana (HV) (74,2 por cento) da hanseníase foi a mais prevalente e o olho seco (66,7 por cento) foi mais freqüente nesta forma clínica da doença. CONCLUSAO: A prevalência de olho seco foi maior no grupo de hansenianos, apesar de não ter havido diferença significativa.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Leprosy/epidemiology , Tears/physiology , Dry Eye Syndromes/epidemiology , Age Factors , Brazil/epidemiology , Case-Control Studies , Chi-Square Distribution , Fluorescent Dyes , Prevalence , Rose Bengal , Sex FactorsABSTRACT
Objetico: Determinar a prevalencia de olho seco em portadores de hanseniase do Hospital de Dermatologia Sanitaria de Goiania, comparando-se a um grupo controle. Desenho: Estudo de prevalencia. Material e metodos: A amostra do presente estudo inclui 70 portadores de hanseniase, do Hospital de Dermatologia Sanitaria de Goiania, e 30 individuos no grupo controle, da Fundacao Banco de Olhos de Goias, ambos localizados em Goiania-GO. Foram realizados exeme oftalmologico e testes de Schirmer I, break-up time (BUT) e rosa bengala em todos estes individuos em uma unica avaliacao. Resultados: Quarenta e quatro (63,0%) portadores de hanseniase eram do sexo masculino e 22 73,3%) individuos do grupo controle, do sexo feminino (p=0,001). A idade medica dos hansenianos foi de 61,1+-12,5 anos e no grupo controle, 55,7+-9,6 anos. Quinze (21,4%) hansenianos e quatro (13,3%) individuos deo grupo controle apresentaram diagnostico de olho seco (p=0,429) A forma virchowiana (74,2%) da hanseniase foi a mais prevalente e o olho seco (66,7%) foi mais frequente nesta forma clinica da doenca. Conclusao: A prevalencia de olho seco nos portadores de hanseniase foi semelhante a encontrada nos individuos do grupo controle