[Osteitis leprosa multiplex cystica--an early symptom of lepromatous leprosy]. / Ostitis leprosa multiplex cystica--ein Frühsymptom der lepromatösen Lepra.

Bone lesions of the finger in a 20-year-old leprosy patient are described to show their diagnostic value. The aetiological differences between specific (caused by Mycobacterium leprae itself) and unspecific osseal changes are morphologically noticeable in morbus Hansen. The X-ray picture shows cystic lightening by granulomatous destruction and distal absorption of the bone. These lesions are typical, and radiological investigations might be the first step in the diagnosis of leprosy. In our case, ostitis leprosa multiplex cystica, an early, specific bone lesion, was predominant.

[Bone changes in Hansen's disease]. / Knochenveränderungen bei Morbus Hansen.

Bone lesion is a frequent organic manifestation in leprosy. Osseal destructions caused by granulomatous process induced by M. leprae are so-called specific lesions in contrast to non-specific lesions based on nerval or arterial diseases. The specific osseal alterations are characterized by cystic brightenings in roentgenograms while non-specific osseal changes show absorption to bone structure as akroosterolysis and osteoporosis. Typical radiologic findings in different stages of mutilation are demonstrated.

Skeletal deformities of the denervated hand in Hansen's disease.

Skeletal deformities of the denervated hand are subtle in their development and pose a more formidable problem than do primary deformities of Hansen's disease. Basic osseous changes consist of concentric, longitudinal, or the longitudinal varying methods of absorption. Knowledge of their pathogenesis provides the basis for their management. Prevention of deformity and conservative management of secondary complications are necessary to salvage as much of the hand as possible.